小肠神经内分泌肿瘤2例并文献回顾

doi:10.6040/j.issn.1671-7554.0.2019.913

摘要/Abstract

摘要： 目的探讨小肠神经内分泌肿瘤(SI-NETs)流行病学、发病机制、临床表现、影像学选择、病理特点及治疗方法,分析其生物学行为及预后情况。方法对收治的2例小肠神经内分泌癌患者的临床病理资料进行分析。结果 SI-NETs发生机制尚不明确,以遗传因素为主,本病恶性程度偏低,无早期特异性临床表现,发病时多为晚期,预后不佳。结论进一步研究SI-NETs分子发生机制及预后预测生物标志物为确切依据的优选治疗策略,对本病早期诊断治疗及改善预后具有重要意义。

关键词: 小肠, 神经内分泌肿瘤, 临床特点, 分子标志物

Abstract: Objective To explore the epidemiology, pathogenesis, clinical manifestation, imaging selection, pathological characteristics and treatment of small intestinal neuroendocrine tumors(SI-NETs), and to analyze the biological behavior and prognosis. Methods The clinicopathological data of 2 cases of SI-NETs were reviewed. Results The pathogenesis of SI-NETs remained unclear, mainly due to genetic factors. The malignant degree of SI-NETs was low, and there was no early specific clinical manifestation. The onset of the disease was late, and patients generally had poor prognosis. Conclusion Further study of the molecular mechanism and prognostic biomarkers of SI-NETs can provide information for the choice of optimal treatment strategy, and is of great significance for the early diagnosis, treatment and prognosis.

Key words: Small intestine, Neuroendocrine neoplasms, Clinical feature, Molecular marker

中图分类号:

R735.3+2

夏丹丹,王惠宇,许隽颖,刘超英,王润洁. 小肠神经内分泌肿瘤2例并文献回顾[J]. 山东大学学报 (医学版), 2020, 58(1): 87-90.

XIA Dandan, WANG Huiyu, XU Junying, LIU Chaoying, WANG Runjie. Small intestinal neuroendocrine tumors: report of 2 cases and literature review[J]. Journal of Shandong University (Health Sciences), 2020, 58(1): 87-90.

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