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山东大学学报 (医学版) ›› 2020, Vol. 58 ›› Issue (1): 81-86.doi: 10.6040/j.issn.1671-7554.0.2019.764

• • 上一篇    

隐源性机化性肺炎9例并文献复习

王化生1, 欧仁杰2,王默3,白龙振2,李英杰2,孙超2,王永梅4   

  1. 1. 山东大学第二医院胸外科, 山东 济南 250033;2. 山东玲珑英城医院胸外科, 山东 招远 265400;3. 山东大学附属省立医院血管外科, 山东 济南 250021;4. 山东大学第二医院心内科, 山东 济南 250033
  • 发布日期:2022-09-27
  • 通讯作者: 王永梅 . E-mail: xinzang2012@126.com

Clinical features of 9 cases of cryptogenic organizing pneumonia and literature review

WANG Huasheng1, OU Renjie2, WANG Mo3, BAI Longzhen2,LI Yingjie2, SUN Chao2, WANG Yongmei4   

  1. 1. Department of Thoracic Surgery, The Second Hospital of Shandong University, Jinan 250033, Shandong, China;
    2. Department of Thoracic Surgery, The Shandong Linglong Yingcheng Hospital, Zhaoyuan 265400, Shandong, China;
    3. Department of Vascular Surgery, Shandong Provincial Hospital Affilited to Shandong University, Jinan 250021, Shandong, China;
    4. Department of Cardiology, The Second Hospital of Shandong University, Jinan 250033, Shandong, China
  • Published:2022-09-27

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摘要： 目的 探讨在临床放射学诊断上比较独特,易被误诊误治的隐源性机化性肺炎(COP)的临床特点。 方法 回顾性分析通过症状、病史、影像学和病理检查诊断和治疗的9例COP患者临床资料,进行总结分析。 结果 本级病例症状以咳嗽(66.7%)和胸闷(55.6%)多见;实验室检查示CRP(63.0±92.6)mg/L和ESR(35.5±26.3)mm/h明显升高;胸部CT以双侧或者单侧斑片状或弥漫性实变影(55.6%)多见,通常分布于肺周边部位,游走性是特征性表现;病理特点为肺泡和细支气管腔内充满疏松成纤维细胞结缔组织栓,呈圆形或哑铃形;对皮质类固醇治疗敏感,预后良好。 结论 COP临床症状虽不特异,但胸部影像学有特征性表现,尽早应用皮质类固醇治疗,预后良好。

关键词: 隐源性机化性肺炎, 临床特点, 放射影像特征, 皮质类固醇

Abstract: Objective To summarize cryptogenic orgenizing pneumonia(COP)s clinical and radiographic features. Methods Nine cases COP were reviewed. Their clinical presentation, radiographic and pathology features were analyzed. Results Cough(66.7%)and chest tightness(55.6%)were the most common symptoms in those patients. CRP and ESR were increased distinctly. Chest CT was characterized by bilateral or unilateral patchy or dffuse con-solidation(55.6%), and migration was its characteristic radiographic feature. In pathological staining, the alveoli and bronchioles were filled with loose fibroblast connective tissue thrombus, which was round or dumbbell-shaped. COP was sen-sitive to corticosteroid therapy, and had a good outcome. Conclusion COP has its own radiographic characteristics and sensitive to corticosteroid treatment. Attention should be paid to the disease to avoid misdiagnosis and mistreatment.

Key words: Cryptogenic organizing pneumonia, Clinical features, Radiographic characteristics, Corticosteroid

中图分类号: 

  • R563
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