住院肺结核合并糖尿病患者流行病学特征

doi:10.6040/j.issn.1671-7554.0.2015.395

摘要/Abstract

摘要： 目的分析南京市胸科医院住院肺结核合并糖尿病(PTB-DM)患者的流行病学特征,为改善预后、疫情防控提供参考。方法纳入2013年8月至2014年7月在南京市胸科医院结核科住院治疗的194例确诊PTB-DM患者,同期住院单纯肺结核患者1 262例作为对照。采用率和构成比描述肺结核患者中糖尿病患病率及临床特点,探讨其可能相关影响因素。结果住院肺结核患者糖尿病患病率为13.32%;PTB-DM患者平均年龄50岁,以农民居多,经济收入较低,受教育程度差,离异或丧偶比例高,多数存在吸烟嗜好;PTB-DM患者临床症状突出,血糖控制差,痰结核分枝杆菌阳性率(70.62%)、肺部空洞率(72.16%)、不良转归率(12.22%)均显著高于单纯肺结核患者(χ2分别为55.143、49.124、8.99, P均<0.05)。结论住院肺结核患者糖尿病患病率高、临床症状重,应重视相关危险因素,加强大规模双向筛查工作,这对改善预后、减少传染源、控制结核病疫情等具有重大意义。

关键词: 糖尿病, 患病率, 流行病学, 肺结核, 临床特点

Abstract: Objective To analyze the epidemiological features of inpatients suffered from pulmonary tuberculosis with diabetes mellitus(PTB-DM)in Nanjing Chest Hospital, and to provide references for improving prognosis and controlling the epidemic of tuberculosis. Methods A total of 194 cases of PTB-DM inpatients in Nanjing Chest Hospital from August 2013 to July 2014 were enrolled, and 1 262 inpatients with pure pulmonary tuberculosis at the same period were as control. The prevalence and clinical features of the PTB-DM inpatients were described with rate and composition proportion, and the related factors were further discussed. Results Prevalence of PTB-DM was 13.32%. The average age of PTB-DM patients was 50 years old. Most of the PTB-DM patients were farmers with low economic income and poor education level. Most of the PTB-DM patients had high divorced or widowed ratios and smoking habit. The PTB-DM patients had bad blood glucose control and more serious clinical symptoms. Compared with the pure pulmonary tuberculosis patients, PTB-DM patients had higher positive rate of sputum mycobacterium tuberculosis(70.62%), lung cavity rate(72.16%)and poor prognosis rate(12.22%)with χ2 being respective 55.143, 49.124, and 8.99(all P<0.05). Conclusion The PTB-DM inpatients have serious clinical symptoms. PTB-DM associated risk factors should be paid attention to and large-scale and bi-directiona1 screening for pulmonary tuberculosis and diabetes mellitus be strengthened to improve prognosis, reduce infection and control the epidemic of tuberculosis.

Key words: Pulmonary tuberculosis, Diabetes mellitus, Clinical features, Epidemiology, Prevalence

中图分类号:

R521

尹小芳,葛海波. 住院肺结核合并糖尿病患者流行病学特征[J]. 山东大学学报（医学版）, 2016, 54(1): 58-61.

YIN Xiaofang, GE Haibo. Epidemiological features of inpatients suffered from pulmonary tuberculosis with diabetes mellitus[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2016, 54(1): 58-61.

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