山东大学学报 (医学版) ›› 2024, Vol. 62 ›› Issue (8): 117-124.doi: 10.6040/j.issn.1671-7554.0.2024.0660
• • 上一篇
刘婧敏1,阿丽娜·伊力哈木江1,古丽努尔·阿吾提2,3
LIU Jingmin1, Alina·YILIHAMUJIANG1, Gulinuer·AWUTI2,3
摘要: 目的 探讨抗菌光动力疗法(antimicrobial photodynamic therapy, aPDT)治疗口源性口臭的疗效。 方法 为了解决“aPDT或aPDT联合刮舌器(tongue scraper, TS)治疗口源性口臭是否比单独用刮舌器更有效”的问题,应用oral halitosis或oral malodor或bad breath和PDT或 photodynamic inactivation 或photodynamic therapy或photodynamic antimicrobial chemotherapy对PubMed、Cochrane 图书馆从建库开始到2024年2月29日的所有文献进行了无语言限制的检索。排除标准包括:非人类实验、体外研究、重复报道的文献、数据不详者、不使用 OralChromaTM作为测量仪器的综述、病例报告或实验方案。 结果 最后纳入了8项随机对照试验,提取数据并进行数据处理后显示:在口臭治疗后立即降低硫化氢浓度方面,aPDT或aPDT+TS比TS具有更好的效果。还有一项研究报告显示:aPDT治疗后细菌载量下降,而TS治疗后细菌载量增加,这表明aPDT对口腔微生物的效果强于TS。 结论 aPDT或aPDT+TS对口源性口臭有效,但还需要更多、更严谨的试验和更进一步的研究,来探索不同时间间隔下aPDT治疗口源性口臭的临床效果。
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