关键词: 2型糖尿病, 冠心病, 冠状动脉造影, 白蛋白尿

Abstract:

Objective To investigate the features of coronary artery affection and the relationship between coronary artery affection degree and albuminuria intype 2 diabetic patients combined with coronary heart disease (CHD).    Methods CHD patients were proved by coronary arteriongraphy. 64 patients with type 2 diabetes in combination with CHD were enrolled in group A and 98 patients with simple CHD served as group B. Patients of group A were subdivided into 3 groups based on scalar of the stenotic coronary artery, viz 1 ramus, 2 rami and 3 rami affection groups, and urinary albumin level was determined. In group A, age, course of DM, BMI, BP, BS, GHbA1c, blood-fat, UAL serving as iv, and affection sum and stenosis index serving as dv, ran polynary gradual regressive analysis.  Results There were statistical differences in BMI, FBS, TG, HDL-C, and UAL between group A and B (P<0.05). Compared with group B, group A had increased IN of poly-coronary artery affection, IN of diffuse affection, affection sum and stenosis index(P<0.05). In group A, there were statistical differences in UAL among the3 subsets (P<0.05). Affection sum and stenosis indexes had a positive co-linearity with urinary albumin(r=0.548?3, 0.576?2, P<0.05).  Conclusion  In type 2 diabetic patients in combination with CHD, coronary artery affection is extensive, diffuse and severe. An increase of urinary albumin is a risk factor for type 2diabetic patients who will get coronary heart disease and can reflex the degree of coronary artery affection to some extent.

Key words: Type 2 diabetes mellitus; Coronary heart disease; Coronary arteriongraphy; Albuminuria