Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (8): 22-27,33.doi: 10.6040/j.issn.1671-7554.0.2020.0399

• Special Topic on Brain Science and Brain Like Intelligence • Previous Articles     Next Articles

Advances on the treatment of Alzheimer's disease with deep brain stimulation

Xinguang YU*(),Yanyang ZHANG   

  1. Department of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing 100853, China
  • Received:2020-03-20 Online:2020-08-07 Published:2020-08-07
  • Contact: Xinguang YU E-mail:yuxinguang_301@163.com

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Abstract:

Alzheimer's disease (AD) has been increasingly considered as a large-scale network disconnection syndrome. Currently, AD remains unchecked, and the economic burden on society is huge. Deep brain stimulation (DBS) engaging circuits and networks in the brain of AD patients is proved potentially therapeutic, but still in the infant stage. This article reviews the indications, stimulation targets and parameters, mechanism and future trends of DBS in the treatment of AD.

Key words: Alzheimer's Disease, Deep brain stimulation, Brain network, Neuroimaging

CLC Number: 

  • R741
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