Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (11): 130-136.doi: 10.6040/j.issn.1671-7554.0.2018.236

Previous Articles    

Internal exposure of volatile organic compounds in residents near an industrial base

CUI Yongxue1, LI Xinwei1, CUI Liangliang1, LIU Zhong2, MENG Zhonghua2, ZHOU Jingwen1   

  1. 1. Department of Environmental Health;
    2. Department of Physical and Chemical Testing, Jinan Center for Disease Control and Prevention, Jinan 250021, Shandong, China
  • Published:2022-09-27

Abstract: Objective To detect the internal exposure of volatile organic compounds(VOCs)in residents near an industrial base and residents of control area, and to analyze whether the industrial base had caused an increase in exposure levels among nearby residents. Methods Residents near the industrial base A were selected as the exposure group. At the same time, a 1∶1 matching(age ±3, same sex)control group was established. The basic information of residents was collected; VOCs(benzene compounds and halo-hydrocarbons)in whole blood were detected by the method of purge and trap; and the differences were statistically analyzed. Results The detection rate of toluene in exposure group was higher than the control group. The medians of concentration of benzene, ethylbenzene, o-xylene, m-/p-xylene, tetrachloromethane, bromodichloromethane and trichloro ethylene in exposure group were all higher than control group, and the same was observed on the detection rate. Conclusion Industrial base A raised the internal exposure levels of ethylbenzene, o-xylene, and m-/p-xylene of nearby residents. It is recommended to propagandize the biohazard of trichloroethylene and the preventive measures.

Key words: Volatile organic compounds, Purge and trap, Internal exposure, Benzene compounds, Halo-hydrocarbons

CLC Number: 

  • R991
[1] 中华人民共和国环保部办公厅. “十三五”挥发性有机物污染防治工作方案[EB/OL].(2017-09-14)[2018-09-20]. http://www.mee.gov.cn/gkml/hbb/bwj/201709/t20170919_421835.htm.
[2] United States Environmental Protection Agency. Volatile organic compounds impact on indoor air quality[EB/OL].(2017-11-06)[2018-09-20]. https://www.epa.gov/indoor-air-quality-iaq/volatile-organic-compounds-impact-indoor-air-quality#Health_Effects.
[3] 中华人民共和国财政部.关于印发《挥发性有机物排污收费试点办法》的通知[EB/OL].(2015-06-18)[2018-02-23]. http://szs.mof.gov.cn/zhengwuxinxi/zhengcefabu/201506/t20150625_1261143.html.
[4] 王玮,李成思.大气污染防治法修改了什么?专访中国环境科学研究院副院长柴发合[EB/OL].(2014-09-18)[2018-09-20]. http://www.mee.gov.cn/gzfw_13107/zcfg/zcfgjd/201605/t20160522_343073.shtml.
[5] 陈枢青. 环境污染物内暴露剂量测量的应用研究现状及其前景[J]. 浙江大学学报(医学版), 2009, 38(3): 226-228.
[6] 中国气象局公共气象服务中心. 中国天气网(济南气候背景分析)[EB/OL].(2018-02-23)[2018-02-23]. http://www.weather.com.cn/cityintro/101120101.shtml.
[7] Blount BC, Kobelski RJ, McElprang DO, et al. Quantification of 31 volatile organic compounds in whole blood using solid-phase microextraction and gas chromatography-mass spectrometry[J]. J Chromatogr B Analyt Technol Biomed Life Sci, 2006, 832(2):292-301.
[8] Ashley DL, Bonin MA, Cardinali FL, et al. Determining volatile organic compounds in human blood from a large sample population by using purge and trap gas chromatography/mass spectrometry[J]. Anal Chem, 1992, 64(9):1021-1029.
[9] 邹宇,邓雪娇,李菲.广州市大气中苯系物健康风险评价[J]. 环境与健康杂志, 2014, 31(12):1079-1081. ZOU Yu, DENG Xuejiao, LI Fei. Health risk assessment of atmospheric benzene compounds in Guangzhou[J]. Journal of Environment and Health, 2014, 31(12):1079-1081.
[10] 雷雅静, 朱银焕, 施卫星, 等. 几种环境污染物质在体检人群中的内暴露水平[J]. 浙江大学学报(医学版), 2013, 42(1):14-18. LEI Yajing, ZHU Yinhuan, SHI Weixing, et al. Determination of several environmental contaminants in human body[J]. Journal of Zhejiang University(Medical Sciences), 2013, 42(1):14-18.
[11] Statistics Canada. Concentrations of selected environmental chemicals in the Canadian population[EB/OL].(2017-08-24)[2018-02-23]. http://www.statcan.gc.ca/pub/82-627-x/82-627-x2017001-eng.htm.
[12] 李湉湉, 程艳丽, 颜敏, 等. 贵阳市室内空气中苯和甲醛的健康风险评价[J]. 环境与健康杂志, 2008, 25(9):757-759. LI Tiantian, CHENG Yanli, YAN Min, et al. human health risk assessment of benzene and formaldehyde in different indoor environment in Guiyang city[J]. Journal of Environment and Health, 2008, 25(9):757-759.
[13] United States Environmental Protection Agency. Risk assessment: guidance for superfund volume 1 human health evaluation manual(PartA)[EB/OL].(2010-04-01)[2018-02-23].https://www.epa.gov/sites/production/files/2015-09/documents/rags_a.pdf.
[14] United States Environmental Protection Agency. Guidelines for carcinogen risk assessment[EB/OL].(2005-03-01)[2018-02-23]. https://www.epa.gov/risk/guidelines-carcinogen-risk-assessment.
[15] 中华人民共和国卫生部, 中国国家标准化委员会. GB/T 5750.10-2006生活饮用水标准检验方法消毒副产物指标[S]. 北京: 中国标准出版社, 2007.
[16] 周志荣, 王红伟, 张淼, 等. 北京市生活饮用水及家用净水设备出水中挥发性有机物的水平调查[J]. 环境与健康杂志, 2017, 34(5):420-422. ZHOU Zhirong, WANG Hongwei, ZHANG Miao, et al. Investigation of volatile organic compounds in tap water and purified water produced by water treatment units in Beijing[J]. Journal of Environment and Health, 2017, 34(5):420-422.
[17] 李新伟, 崔永学, 张扬, 等. 济南市市政供水三氯甲烷和四氯化碳含量及风险评估[J]. 环境卫生学杂志, 2018, 8(1):42-45. LI Xinwei, CUI Yongxue, ZHANG Yang, et al. Assessment on the levels and health risks of chloroform and carbon tetrachloride in municipal water supplies in Jinan[J]. Journal of Environmental Hygiene, 2018, 8(1):42-45.
[18] 黄伯越, 冯海飞, 蓝结群, 等. 一起急性三氯甲烷中毒事故调查[J]. 职业与健康, 2008, 24(18):1876-1877. HUANG Boyue, FENG Haifei, LAN Jiequn, et al. Investigation of a case of acute trichloromethane poisoning[J]. Occupation and Health, 2008, 24(18):1876-1877.
[19] 邵迪初. 一起三氯甲烷作业工人肝脏损害调查分析[J]. 工业卫生与职业病, 2001, 27(6):362-363.
[20] 翟延龙. 城市饮用水水源四氯化碳检测结果探究[J]. 世界最新医学信息文摘(连续型电子期刊), 2015,(60):100, 104.
[21] 李迎玲, 张金方, 高瑞林, 等. 城市饮用水水源四氯化碳监测结果分析[J]. 现代预防医学, 2007, 34(5):898, 900. LI Yingling, ZHANG Jinfang, GAO Rinlin, et al. The analysis on the carbon tetrachloride examination result from headwaters of the citys drinking water[J]. Modern Preventive Medicine, 2007, 34(5):898, 900.
[22] 廖静. 一溴二氯甲烷的微核效应及对细胞增生的机制探讨[D]. 武汉:华中科技大学, 2013.
[23] 魏建荣, 王振刚. 饮用水中消毒副产物研究进展[J]. 卫生研究, 2004, 33(1):115-118. WEI Jianrong, WANG Zhengang. Study advance and control measure on disinfection by-products in drinking water[J]. Journal of Hygiene Research, 2004, 33(1):115-118.
[24] 叶必雄, 王五一. 饮用水消毒副产物暴露评价研究进展[J]. 卫生研究, 2009, 38(4):495-499. YE Bixiong, WANG Wuyi. Advances of study on assessing exposure to disinfection by-products in drinking water[J]. Journal of Hygiene Research, 2009, 38(4):495-499.
[25] 黄汉林, 李来玉, 陈秉炯. 广东省三氯乙烯职业危害新问题研究进展[J]. 中国职业医学, 2002, 29(3):2-3.
[26] 余新天, 陈伟武, 朱志良, 等. 三氯乙烯职业危害的预防与控制[J]. 中华劳动卫生职业病杂志, 2014, 32(2):131-132.
[27] Prout MS, Provan WM, Green T. Species differences in response to trichloroethylene. I. Pharmacokinetics in rats and mice[J]. Toxicol Appl Pharmacol, 1985, 79(3):389-400.
[28] 国家食品药品监督管理总局. 世界卫生组织国际癌症研究机构致癌物清单[EB/OL].(2017-10-27)[2018-09-20]. http://samr.cfda.gov.cn/WS01/CL1991/215896.html.
No related articles found!
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
No Suggested Reading articles found!