Journal of Shandong University (Health Sciences) ›› 2025, Vol. 63 ›› Issue (10): 20-26.doi: 10.6040/j.issn.1671-7554.0.2024.0941

• Special Topic on EndometriosisAssociated Pain • Previous Articles    

Current status of diagnosis and treatment of endometriosis in perimenopause and postmenopause

ZHAO Shurui, ZHAO Ye   

  1. Department of Gynecology, First Hospital of Shanxi Medical University, Taiyuan 030001, Shanxi, China
  • Published:2025-10-17

Abstract: Endometriosis is an estrogen-dependent disease, which often occurs in women of reproductive age, and is rare in perimenopausal and postmenopausal women. The main manifestations are chronic pelvic pain, infertility, mass and nodules, among which secondary pelvic pain is the most common reason for patients to seek treatment. In 1942, Edgar Haydon reported the first case of endometriosis in a 78-year-old postmenopausal woman, and since then, there has been a growing number of research on endometriosis in this age group. At present, many scholars believe that the lesions in perimenopausal and postmenopausal endometriosis mainly originate from incompletely atrophic remnants of premenopausal endometriosis, but the exact etiology remain unclear. Standardized diagnosis or treatment protocols for the treatment and management of patients with endometriosis are still lacking. This review systematically summarizes and interprets the characteristics, clinical problems, treatment methods and long-term management of perimenopausal and postmenopausal endometriosis patients, aiming to improve clinicians understanding and treatment capabilities in treating perimenopausal and postmenopausal endometriosis patients.

Key words: Endometriosis, Endometriosis associated-pain, Perimenopause, Postmenopause

CLC Number: 

  • R711.71
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