Journal of Shandong University (Health Sciences) ›› 2025, Vol. 63 ›› Issue (10): 13-19.doi: 10.6040/j.issn.1671-7554.0.2024.0955

• Special Topic on EndometriosisAssociated Pain • Previous Articles    

Research progress on characteristics and treatment of various endometriosis-associated pain

XUE Ming1,2, LIANG Jing1, LING Bin1   

  1. 1. Department of Obstetrics and Gynecology, China-Japan Friendship Hospital, Beijing 100029, China;
    2. Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
  • Published:2025-10-17

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Abstract: Endometriosis is a common chronic condition among women of reproductive age, with an incidence rate as high as 10%. Pain is its most prominent symptom and the most frequent reason for medical consultation, affecting approximately 70%-80% of patients to varying degrees. Endometriosis can involve all tissues and organs within the pelvis, as well as multiple locations and organs outside the pelvis, including the respiratory, digestive, urinary, and nervous systems, causing pain with diverse characteristics and locations. The pain associated with endometriosis is influenced by a range of factors such as inflammatory stimulation, neuropathic conditions, and psychological factors, and is characterized by imprecise localization and varied symptoms. The chronic and recurrent nature of this pain significantly impacts patients physical and mental health, as well as their quality of life. Management of endometriosis-related pain requires a comprehensive consideration of the patients pathological characteristics, type of pain, and psychological state to develop a personalized treatment plan. In the future, with advancements in drug development and surgical techniques, the management of endometriosis pain will become more humane, personalized, and comprehensive, offering patients better treatment outcomes and improved quality of life.

Key words: Endometriosis, Endometriosis-associated pain, Pain management, Drug therapy

CLC Number: 

  • R711.71
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