Journal of Shandong University (Health Sciences) ›› 2023, Vol. 61 ›› Issue (9): 94-100.doi: 10.6040/j.issn.1671-7554.0.2023.0351

• Clinical Medicine • Previous Articles     Next Articles

Therapeutic effects of SpyGlass DS system combined with endoscopic retrograde cholangiopancreatography(ERCP)on patients with choledocholithiasis

HAN Zhuoxing, LIN Hui, DUAN Shigang, YE Zhirong, CHEN Xuanting, LIN Kangqiang   

  1. Department of Hepatobiliary and Pancreatic Surgery, The Second Affiliated Hospital of Guangdong Medical University, Zhanjiang 524000, Guangdong, China
  • Received:2023-04-25 Published:2023-10-10

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Abstract: Objective To investigate the effects of SpyGlass DS system combined with endoscopic retrograde cholangiopancreatography(ERCP)on patients with choledocholithiasis. Methods Clinical data of patients who received SpyGlass DS combined with ERCP(n=23, experimental group)and patients who received ERCP only(n=51, control group)were collected. The operation indicators and outcomes, Oddi sphincter base pressure, peak systolic blood pressure and systolic frequency, as well as differences in the expression levels of serum alanine aminotransferase(ALT), aspartate aminotransferase(AST)and total bilirubin(TBil)were analyzed. Results Compared with the control group, the experimental group had longer operation time, higher hospitalization expenses, shorter hospital stay(P<0.05), higher stone clearance rate(95.65% vs 72.55%, P<0.05), and lower incidence of postoperative pancreatitis(8.70% vs 21.57%, P>0.05). The indicators of sphincter and hepatobiliary function in experimental group and control group were decreased after surgery, and the sphincter base pressure, peak systolic blood pressure and systolic frequency of experimental group were higher than those of control group(P<0.05). There were no significant differences in the expression levels of ALT, AST and TBil between the two groups(P>0.05). Conclusion SpyGlass DS system has a good application effect in ERCP lithotomy. It may be used in clinical practice as an effective surgical method for the treatment of choledocholithiasis.

Key words: SpyGlass DS system, Endoscopic retrograde cholangiopancreatography, Choledocholithiasis, Oddi sphincter function

CLC Number: 

  • R576
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