Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (7): 50-56.doi: 10.6040/j.issn.1671-7554.0.2020.1715

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Effects of bedside lung ultrasonography and lung ultrasonography score in the diagnosis and treatment of 70 cases of neonatal respiratory distress syndrome

LIU Xiao1, GUO Xinyuan2, ZHANG Dejian2, LI Qi2, LI Ning1, XUE Jiang2   

  1. 1. Department of Anesthesiology;
    2. Department of Neonatology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan 250033, Shandong, China
  • Published:2021-07-16

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Abstract: Objective To investigate the effects of bedside lung ultrasonography(LUS)and LUS scores on diagnosing neonatal respiratory distress syndrome(NRDS)and evaluating the pharmacological effects of pulmonary surfactant(PS). Methods A total of 70 neonates who were diagnosed with NRDS were allocated to the observation group, while the other 70 without lung diseases were allocated to the control group. The chest surface reflection was divided to 12 zones. NRDS signs in LUS and LUS scores were recorded. Bedside LUS was performed before PS treatment in the observation group, while LUS was performed after enrollment in the control group. The LUS results between two groups were compared to evaluate the diagnostic value of LUS in NRDS neonates. A total of 60 newborns in the observation group who need PS underwent another bedside LUS examination at 12 h after PS application. NRDS signs in LUS and LUS scores were compared before and after PS application, and the blood gas analysis and chest X-ray results were also compared. The role of LUS in the therapeutic effect of PS was also evaluated. Results The detection rate of NRDS signs in LUS and LUS score in observation group were significantly higher than those in control group(P<0.001). LUS score showed a high sensitivity(98.57%)and specificity(100%)in the diagnosis of NRDS, and it predicted the use of PS in neonates with NRDS with a high sensitivity(90.00%)and specificity(90.00%). NRDS signs in the observation group reduced significantly 12 h after PS application than before, and LUS scores also decreased(P<0.001). Conclusion Bedside LUS is accurate and reliable in diagnosis of NRDS. The effects of PS can be accurately evaluated by real-time bedside LUS and LUS scores.

Key words: Bedside lung ultrasonography, Lung ultrasonography score, Neonatal respiratory distress syndrome, Pulmonary surfactant

CLC Number: 

  • R722
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