Journal of Shandong University (Health Sciences) ›› 2020, Vol. 58 ›› Issue (3): 113-117.doi: 10.6040/j.issn.1671-7554.0.2019.1286

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Effect of tailored bowel preparation on bowel preparation quality

LI Pan1,2, LI Yueyue1,2, LI Yanqing1,2,3   

  1. 1. Department of Gastroenterology;
    2. Laboratory of Translational Gastroenterology;
    3. Robot Engineering Laboratory for Precise Diagnosis and Therapy of GI Tumor, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Online:2020-03-10 Published:2022-09-27

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Abstract: Objective To investigate the effect of Dik VK predictive model in guiding bowel preparation. Methods A total of 409 patients who underwent colonoscopy were randomly assigned to tailored group and control group. Patients in the tailored group were assessed with Dik VK predictive model. Those with high risk of inadequate bowel preparation were prescribed a regimen of 4L polyethylene glycol(PEG), while those with low risk were given a normal dose of 2L PEG. Patients in the control group were prescribed a normal dose of 2L PEG. The bowel preparation quality and poly detection rate were recorded during colonoscopy. Continuous variables were analyzed using student-t test and categorical variables were analyzed using Pearson χ2 test. Results Seven patients cancelled colonoscopy appointment for personal reasons and finally 402 patients received colonoscopy and were included into ITT analysis(202 cases in tailored group, 200 cases in control group). The tailored group had higher adequate bowel preparation rate than the control group(89.6% vs 77.5%, P=0.002), higher total Boston Bowel Preparation Score(BBPS)(7.12±1.43 vs 6.64±1.71, P=0.002), higher scores for the separate three colon segments(P=0.004, P=0.030, P=0.022), and larger number of polyps detected per patient(0.74±1.23 vs 0.49±0.87, P=0.020). There were no differences in adverse reactions and degree of satisfaction between the two groups. Conclusion Tailored bowel preparation guided by the predictive model for inadequate bowel preparation significantly improves the overall quality of bowel preparation.

Key words: Bowel preparation, Tailored bowel preparation, Boston Bowel Preparation Score, Predictive model, Colonoscopy

CLC Number: 

  • R574
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