Abstract: Objective To investigate the effects of implanted cardiac permanent pacemaker on anxiety or depression associated with bradyarrhythmia, and to explore the related risk factors. Methods A total of 212 outpatients with bradyarrhythmia were selected and according to the inclusion and exclusion criteria 198 patients were finally enrolled. According to the comprehensive assessment and patient willingness, patients were divided into control group(n=96)and pacemaker group(n=102). Each patients basic information, medical history, blood biochemical indexes, 24 h Holter monitoring results, and echocardiography results were acquired, and hamilton anxiety scale and hamilton depression scale were completed. The above examinations and questionnaires were completed again after 3 months. The data were collected and compared. Results The installation of cardiac permanent pacemaker significantly reduced anxiety or depression symptoms associated with bradyarrhythmia(P<0.001). Anxiety was significantly and positively correlated with women, age, wakefulness, syncope, the longest R-R interval, smoking, drinking, hypertension and diabetes(P<0.05). Depression was also remarkably and positively correlated with women, age, wakefulness, syncope and diabetes(P<0.05). Conclusion The implantation of cardiac permanent pacemaker can significantly alleviate symptoms of anxiety or depression associated with bradyarrhythmia.

Key words: Cardiac permanent pacemaker, Heart disease with psychiatric disease, Hamilton Scale, Anxiety, Depression