Journal of Shandong University (Health Sciences) ›› 2019, Vol. 57 ›› Issue (6): 94-99.doi: 10.6040/j.issn.1671-7554.0.2018.1397

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Value of strain ratio of compression elastography and virtual touch tissue quantification in the diagnosis of breast lesions

SHANG Mengmeng1, ZHANG Yan2, CHENG Lin1, SUN Xiao1, SHI Dandan1, MIN Xiang3, LI Jie1   

  1. 1. Department of Ultrasound, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China;
    2. Department of Healthcare, Service Center, Water Resources Department of Shandong Province, Jinan 250013, Shandong, China;
    3. Center of Health Examination, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To compare the diagnostic performances of strain ratio of compression elastography and virtual touch tissue quantification(VTQ)in the differentiation of benign and malignant breast lesions. Methods A total of 49 female patients with 52 breast lesions were enrolled in this study. Both compression elastography and VTQ were performed, and SR and shear wave velocity were measured. Receiver operating characteristic(ROC)curves were used to analyze the diagnostic performances and Z tests were used to compare the area under the curve. Results For the SR method, the AUC, optimal cutoff value, sensitivity, specificity, positive predictive value, negative predictive value(NPV)and accuracy was 0.919, 0.499, 93.6%, 72.0%, 78.8%, 94.7%, and 84.6%, respectively. For the VTQ method, the AUC, optimal cutoff value, sensitivity, specificity, PPV, NPV and accuracy was 0.796, 2.90 m/s, 68.0%, 山 东 大 学 学 报 (医 学 版)57卷6期 -商蒙蒙,等.弹性应变率比值法与声触诊组织量化技术对乳腺肿块的诊断价值 \=-92.6%, 89.5%, 75.8% and 80.8%, respectively. There was no significant difference in AUC between the two methods (Z=1.580, P=0.057). When compression elastography and VTQ were used in combination, the sensitivity, specificity, PPV, NPV and accuracy was 84.0%, 88.9%, 87.5%, 85.7% and 86.5%, respectively. Conclusion Both SR and VTQ are helpful in the(semi-)quantitative evaluation of the stiffness of breast lesions. Their diagnostic performances are similar. The SR method shows higher sensitivity but lower specificity than VTQ. The combination of compression elastography and VTQ can significantly improve the diagnostic performance of ultrasound to differentiate benign and malignant breast lesions.

Key words: Elastography, Strain ratio, Virtual touch tissue quantification, Breast lesion, Ultrasonography

CLC Number: 

  • R445.1
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