JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2017, Vol. 55 ›› Issue (11): 42-46.doi: 10.6040/j.issn.1671-7554.0.2017.141

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Surgical treatment for 61 patients with multiple lung lesions

PENG Yue, FENG Zhen, XIE Hounai, WANG Hui, LI Meng, REN Wangang, LIU Tong, PENG Zhongmin   

  1. Department of Thoracic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China
  • Received:2017-02-14 Online:2017-11-10 Published:2017-11-10

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Abstract: Objective To provide experiences for clinical diagnosis and treatment by analyzing the surgical outcomes for patients with multiple lung lesions. Methods Clinical data of 61 patients with clinical diagnosis of synchronous multiple primary non-small cell lung cancer(SMPLC)were collected from May 2012 to Apr. 2016 in our hospital. The clinicopathologic features, surgical treatment and overall survival(OS)were retrospectively analyzed. Results Among the 61 patients, 47 patients were verified with more than one malignant tumors. Ten patients were verified with only one malignant tumor, and all lesions of the other 4 patients were benign. Forty-one patients were finally diagnosed with SMPLC after surgical treatment. The 1-year and 3-year OS rates were 97.0% and 77.5%, respectively. Smaller dimension of maximal tumor(χ2=10.918, P=0.012), lesions with less solid ingredient(χ2=10.754, P=0.005), lymph nodes metastases negative(χ2=10.234, P=0.001)and earlier TNM stage(χ2=12.068, P=0.007)were correlated with better OS. Conclusion For patients with multiple lung lesions, if the diagnosis of SMPLC can not be excluded and there is no lymph nodes metastases in thoracic computed tomography, surgical treatment can be considered preferentially.

Key words: Multiple lung lesions, Synchronous primary lung cancer, Surgical treatment, Multiple primary non-small cell lung cancer

CLC Number: 

  • R734.2
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