Abstract: Objective To investigate the effect of anticoagulation on the remodeling of residual false lumen after aortic valve replacement of DeBakey type I aortic dissection. Methods Clinical data of 31 patients with DeBakey type I aortic dissection treated during Oct. 2014 and Jun. 2015 were retrospectively analyzed. The patients were divided into two groups, that is, group one(n=20)who underwent surgical repairs with total arch replacement and modified stented elephant trunk technique(Suns Operation), and group two(n=11)who underwent surgical repairs with Suns Operation and aortic valve replacement. About 3 to 6 months after surgery, aortic CT angiography was performed to measure the diameter of the true lumen and aorta in the level of the initial, middle and end of the stent, celiac trunk, superior mesenteric artery and renal artery in each phase. The pre-operation and postoperative ratios of true lumen and aorta were 山 东 大 学 学 报 (医 学 版)54卷12期 -王龙,等.主动脉瓣置换术后抗凝对DeBakeyⅠ型主动脉夹层残余假腔重塑效果的临床影响 \=-calculated, respec-tively. In addition, the false lumen thrombosis was observed. Results There was no significant difference in the preoperative ratio of the true lumen and aorta diameter in the levels of the initial, middle and end of the stent, celiac trunk, superior mesenteric artery and renal artery(P=0.30, 0.94, 0.96, 0.54, 0.83, 0.49)between the two groups. After surgery, there was no significant difference in the ratio of the true lumen and aorta diameter in the 6 levels(P=0.28, 0.16, 0.28, 0.39, 0.44, 0.23)between the two groups. Conclusion Whether the aortic valve is involved has no difference in the lesions of stent and distal aorta. Anticoagulation therapy after aortic valve replacement has no significant effect on the residual false lumen remodeling of DeBakey type I aortic dissection.

Key words: DeBakey type I, Anticoagulation, Residual false lumen, Aortic dissection