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山东大学学报 (医学版) ›› 2019, Vol. 57 ›› Issue (11): 47-51.doi: 10.6040/j.issn.1671-7554.0.2019.542

• • 上一篇    

85例复发性下肢静脉曲张影像学检查相关分析

吴梦涛1,郭亚南1,唐佃俊1,王素珍2,周涛1,李凡东1   

  1. 1.山东大学第二医院血管外科, 山东 济南 250033;2.青岛大学附属医院肝脏移植科, 山东 青岛 266003
  • 发布日期:2022-09-27
  • 通讯作者: 李凡东. E-mail:fandongli90@hotmail.com
  • 基金资助:
    山东省医药卫生科技发展计划(2017WS627);山东大学临床医学院、齐鲁医学院教学改革项目(LCJY-65;qlyxjy-201949)

An analysis of the imaging information of 85 patients with recurrent varicose veins in lower extremity

WU Mengtao1, GUO Yanan1, TANG Dianjun1, WANG Suzhen2, ZHOU Tao1, LI Fandong1   

  1. 1. Department of Vascular Surgery, The Second Hospital of Shandong University, Jinan 250033, Shandong, China;
    2. Department of Liver Transplantation, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, China
  • Published:2022-09-27

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摘要： 目的 探讨与复发性下肢静脉曲张有关联的危险因素。 方法 基于血流动力学回顾性分析山东大学第二医院2013年6月至2018年6月收治复发性下肢静脉曲张患者85例(85条肢体)的临床资料。根据彩色多普勒超声和CT影像学检查结果,分析病例的复发原因。以临床表现-病因学-解剖-病理生理静脉分类系统(clinical, etiological, anatomical, pathophysiological classification, CEAP)的临床分级作为应变量,应用有序Logistic回归,分析应变量与复发原因的相互关系,探讨下肢静脉曲张术后复发的相关危险因素。 结果 85例患者中大隐静脉主干与属支的残留或再通者占37.6%,静脉管腔狭窄或阻塞者占30.6%,穿通静脉功能不全者占23.5%,小隐静脉功能不全者占8.2%。通过Logistic回归分析,穿通静脉功能不全(OR=10.465,95%CI:2.980~36.782,P<0.001)、深静脉系统狭窄(OR=9.554,95%CI: 2.933~31.094,P<0.001)、复发时间(OR=1.684,95%CI:1.335~2.123,P<0.001)以及年龄(OR=0.930,95%CI:0.877~0.985,P=0.014)对复发性下肢静脉曲张的CEAP临床分级的影响差异有统计学意义;而性别(OR=1.068,95%CI:0.439~2.596,P=0.885)和大隐静脉主干残留(OR=0.758,95%CI:0.239~2.406,P=0.638)对复发性下肢静脉曲张的CEAP临床分级差异无统计学意义。 结论 穿通静脉功能不全、深静脉系统狭窄和复发时间是复发性下肢静脉曲张的独立危险因素;年龄因素是复发性下肢静脉曲张的保护因素。

关键词: 静脉曲张, 复发, 血流动力学, 危险因素, 穿通静脉

Abstract: Objective To investigate the risk factors of recurrent varicose veins in lower extremity. Methods The hemodynamic data of 85 patients(85 limbs)with recurrent varicose veins in lower extremity treated during June 2013 and June 2018 were retrospectively analyzed. The color Doppler ultrasound and CT imaging results were analyzed to investigate the causes of recurrence. The classification in clinical, etiological, anatomical, pathophysiological classification(CEAP)was used as the dependent variable. The relationship between the dependent variable and causes of recurrence was analyzed with ordinal logistic regression, and the risk factors of recurrence were explored. Results In 85 patients, 37.6% had residual or recanalization of the great saphenous vein and its branches, 30.6% had venous stenosis or obstruction, 23.5% had penetrating venous insufficiency, and 8.2% had small saphenous vein insufficiency. Logistic regression analysis showed that penetrating venous insufficiency(OR=10.465, 95%CI: 2.980-36.782, P<0.001), deep 山 东 大 学 学 报 (医 学 版)57卷11期 -吴梦涛,等.85例复发性下肢静脉曲张影像学检查相关分析 \=-venous system stenosis(OR=9.554, 95%CI: 2.933-31.094, P<0.001), recurrence time(OR=1.684, 95%CI: 1.335-2.123, P<0.001)and age(OR=0.930, 95%CI: 0.877-0.985, P=0.014)had statistically significant effects on the CEAP classification of recurrent varices, while gender(OR=1.068, 95%CI: 0.439-2.596, P=0.885)and residual great saphenous vein(OR=0.758, 95%CI: 0.239-2.406, P=0.638)had no significant effects. Conclusion Perforating venous insufficiency, deep venous stenosis and recurrence time are independent risk factors while age is a protective factor for recurrent lower extremity varices.

Key words: Varicose veins, Recurrent, Hemodynamics, Risk factors, Perforating vein

中图分类号: 

  • R543.6
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