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山东大学学报 (医学版) ›› 2017, Vol. 55 ›› Issue (12): 36-42.doi: 10.6040/j.issn.1671-7554.0.2017.825

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1 060例脑性瘫痪患者MRI表现及其与临床特征的关系

王耸1,2,程洪斌2,伊龙2,王培申2,孙宪昶3,安沂华1,2   

  1. 1.锦州医科大学武警总医院研究生培养基地, 北京 100039;2.中国人民武装警察部队总医院功能神经外科, 北京 100039;3.中国人民武装警察部队总医院CT科, 北京 100039
  • 出版日期:2017-12-20 发布日期:2022-09-27
  • 通讯作者: 安沂华. E-mail:riveran@163.com

Relationship between magnetic resonance imaging and clinical characteristics of cerebral palsy based on 1 060 cases

WANG Song1,2, CHENG Hongbin2, YI Long2, WANG Peishen2, SUN Xianchang3, AN Yihua1,2   

  1. 1. Postgraduate Training Base, General Hospital of Chinese Peoples Armed Police Forces, Jinzhou Medical University, Beijing 100039, China;
    2. Department of Functional Neurosurgery, the General Hospital of Chinese Peoples Armed Police Forces, Beijing 100039, China;
    3. CT Department, the General Hospital of Chinese Peoples Armed Police Forces, Beijing 100039, China
  • Online:2017-12-20 Published:2022-09-27

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摘要： 目的 探讨脑性瘫痪(脑瘫)患者的磁共振成像(MRI)表现及其与脑瘫类型、高危因素的关系。 方法 回顾性分析病历完整并最终确诊的1 060例脑瘫患者资料,包括基本信息、高危因素、MRI表现等。 结果 1 060例患者中头颅MRI表现异常占82.17%,其中以脑室旁(或周围)白质软化症(PVL)(27.93%)、侧脑室扩大(13.11%)、脑萎缩(10.85%)、髓鞘发育不良(10.28%)及胼胝体发育不良(10.19%)等多见。痉挛型脑瘫患者MRI异常率为83.65%,其中以PVL、侧脑室扩大、髓鞘发育不良多见;不随意运动型患者MRI异常率为60.98%,其中以基底节异常信号、PVL、侧脑室扩大多见;共济失调型脑瘫患者MRI异常率为88.57%,其中以小脑发育不良、胼胝体发育不良、PVL多见;混合型脑瘫患者MRI异常率为75.90%。PVL、侧脑室扩大、脑裂畸形在早产患者中比例较高且差异有统计学意义(P均<0.05);PVL、髓鞘发育不良、局灶性脑缺血在具有缺氧因素患者中比例较高且差异有统计学意义(P均<0.05);基底节异常信号、局灶性脑缺血在具有黄疸因素患者中比例较高且差异有统计学意义(P均<0.05)。 结论 MRI检查是脑瘫患儿的首选辅助检查方法,其结果与患者脑部病变及脑瘫的类型、高危因素密切相关。

关键词: 脑性瘫患, 磁共振成像, 高危因素

Abstract: Objective To analyze the relationship between the brain magnetic resonance imaging(MRI)and cerebral palsy types/risk factors. Methods Information, including age, risk factors, clinical classification and MRI findings, of 1 060 hospitalized patients with cerebral palsy was reviewed. Results Among the 1 060 patients, the abnormal rate of brain MRI results was 82.17%, in which periventricular leukomalacia(PVL)(27.93%), enlargement of the lateral ventricles(13.11%), brain atrophy(10.85%), delayed myelination(10.28%), and abnormal corpus callosum(10.19%)were the common types. The abnormal rate of spastic cerebral palsy was 83.65%, in which PVL, enlargement of the lateral ventricles, and delayed myelination were the commen types. The abnormal rate of dyskinetic cerebral palsy was 60.98%, in which basal ganglia damage, PVL and enlargement of the lateral ventricles were the common types. The abnormal rate of ataxic cerebral palsy was 88.57%, in which cerebellar hypoplasia and abnormal corpus callosum were the common types. The abnormal rate of mixed type was 75.90%. Proportions of PVL, enlargement of the lateral ventricles and schizencephaly were higher in prematurity patients(all P< 0.05). Proportions of PVL, delayed myelina- 山 东 大 学 学 报 (医 学 版)55卷12期 -王耸,等.1 060例脑性瘫痪患者MRI表现及其与临床特征的关系 \=-tion, and focal cerebral ischemia were higher in patients with hypoxia asphyxia(all P<0.05). Proportions of basal ganglia damage and focal cerebral ischemia were higher in patients with pathologic jaundice(both P<0.05). Conclusion MRI has important clinical significance in children with cerebral palsy and its changes are closely related to cerebral palsy types and risk factors.

Key words: Cerebral palsy, Magnetic resonance imaging, Risk factors

中图分类号: 

  • R741
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