大前庭水管综合征婴幼儿患者ASSR和ABR听力学特点

山东大学学报(医学版) ›› 2009, Vol. 47 ›› Issue (8): 89-92.

大前庭水管综合征婴幼儿患者ASSR和ABR听力学特点

马文¹,李海燕¹,于丽²,张建基³，孙晓卫³

1. 山东大学医学院, 济南 250012； 2. 济南市中心医院耳鼻咽喉-头颈外科, 济南 250013；
3. 山东大学齐鲁儿童医院耳鼻咽喉-头颈外科, 济南 250022

收稿日期:2009-01-16 发布日期:2009-08-16
通讯作者: 李海燕,教授,硕士生导师。Email:zxyylhy@163.com
作者简介:马文(1983- ), 女, 硕士研究生,主要从事听力学的研究。

Audiological features of auditory steadystate response and auditory brain stem response in large vestibular aqueduct syndrome

MA Wen¹, LI Haiyan ¹, YU Li ², ZHANG Jianji ³, SUN Xiaowei ³

1. School of Medicine, Shandong University, Jinan 250012, China;
2. Department of Otolaryngology & Head and Neck Surgery,
Jinan Central Hospital, Shandong University, Jinan 250013, China;
3. Department of Otolaryngology, Qilu Children′s Hospital of Shandong University, Jinan 250022, China

Received:2009-01-16 Published:2009-08-16

摘要/Abstract

摘要：

目的利用听觉稳态诱发反应(auditory steadystate response, ASSR)与听性脑干反应(auditory brainstem response, ABR)对大前庭水管综合征(large vestibular aqueduct syndrome, LVAS) 患者进行听力测试，探讨其ASSR和ABR的听力学特点。方法对63例（121耳）确诊为LVAS和同期来我院就诊的20例非LVAS感音神经性聋患儿进行ASSR和ABR测试，分别记录结果，分析并观察其特点。结果LVAS组:ASSR 在0.5～4?kHz阈值呈上升趋势，直至4?kHz反应阈消失，近成直线关系，随低频听阈值的升高，斜率值减小；给出最大刺激频率中，1?kHz反应阈最后消失；当ASSR听阈介于50～80?dBHL时，若ABR以dBnHL为单位，其对应的反应阈数值小于ASSR听阈数值；当ASSR听阈＞100?dBHL时，ABR 109.6?dBnHL已不能引出V波；84耳ABR最大声刺激未引出V波, 其对应ASSR仍可全部或部分频率引出反应阈。非LVAS组:0.5～4?KHz阈值曲线多为平坦型, 2～4?kHz均值与ABR V波反应阈相近。结论大前庭水管综合征患者ASSR 0.5～4?kHz各频率反应阈值呈升高趋势直至消失，其数值与ABR反应阈数值大小具有阶段性改变，其改变区间在80～100?dBHL。

关键词: 大前庭水管综合征；多频听觉稳态诱发反应；听性脑干反应；婴幼儿

Abstract:

To explore characteristics of auditory steadystate response (ASSR) and auditory brainstem response (ABR) in patients with large vestibular aqueduct syndrome (LVAS). MethodsCharacteristics of ASSR and ABR of 63 patients (121ears) with LVAS and 20 patients (40ears) of SHL without LVAS were recorded and analyzed. ResultsIn the LVAS group, ASSR raised in a nearly straightline from 0.5 to 4?kHz thresholds until the threshold of response 4?kHz, with an increase of lowfrequency hearing threshold, the value of the slope was reduced. When the biggest boost in frequency was given, response threshold at 1kHz finally disappeared. When stimulated by the maximal sound of ABR, 84 ears could not draw forth the V wave, whose corresponding ASSR could draw forth the response threshold in all or part frequencies. In the other group, ASSR from 0.5 to 4?kHz thresholds rose mostly in a flat type. The average value of ASSR from 2 to 4?kHz thresholds was similar to that of wave Ⅴ of ABR. ConclusionsASSR of LVAS from 0.5 to 4?kHz thresholds rose in a nearly straightline relationship until the thresholdof response disappeared. The correlation was obvious with an increase of frequency. ASSR and ABR thresholds were significantly correlated and the ASSR thresholds had a stage change with the change interval between 80 and 100?dBHL.

Key words: Large vestibular aqueduct syndrome; Multiple auditory steadystate evoked response (ASSR); Auditory brainstem response (ABR); Infants

中图分类号:

R764.4

. 大前庭水管综合征婴幼儿患者ASSR和ABR听力学特点[J]. 山东大学学报(医学版), 2009, 47(8): 89-92.

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