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山东大学学报(医学版)

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ICU获得性败血症致病菌的临床分析

秦文1,张剑1,李茜2   

  1. 1. 山东大学西校区医院妇科, 山东 济南 250012; 2. 浙江省人民医院ICU科, 浙江 杭州 310000
  • 收稿日期:2006-09-20 修回日期:1900-01-01 出版日期:2007-03-24 发布日期:2007-03-24
  • 通讯作者: 秦文

Pathogenic bacteria of acquired sepicaemia from the ICU: a clinical analysis

QIN Wen1,ZHANG Jian1,LI Qian2   

  1. 1. Department of Gynecology, Western Hospital of Shandong University;2. Department of ICU, Zhejiang Provincial Hospital, Hangzhou 310000
  • Received:2006-09-20 Revised:1900-01-01 Online:2007-03-24 Published:2007-03-24
  • Contact: QIN Wen

摘要: 目的:确定ICU获得性败血症致病菌的种类、药敏情况、临床特征及影响预后的因素。方法:对2003年9月至2006年3月ICU收治的各科患者(入科不到24h死亡、自动出院和转科的患者除外),住ICU期间临床怀疑发生败血症送检血培养或导管标本培养证实的85例92次败血症的病原菌进行回顾性分析。结果:ICU获得性败血症的发病率为9.99%,感染者多存在败血症的易感因素。真菌感染、病程中出现感染性休克及肾衰是影响预后的独立危险因素。致病菌分布和药敏特点:①G-菌分离率最高,以条件致病菌为主;②真菌的分离率明显升高;③耐药率较高。结论:败血症ICU获得性发病率高,真菌感染、病程中出现感染性休克及肾衰是影响败血症预后的独立危险因素。

Abstract: Objective: To explore the category, drug susceptibility, and clinical features of the pathogenic bacteria of acquired septicemia from the ICU and factors affecting prognosis. Methods:The clinical data of the pathogenic bacteria of septicemia confirmed between September 2003 and March 2006 in ICU were retrospectively analyzed. Results: The attack rate of acquired septicemia was 9.99%. Fungal infection, septic shock and renal failure during the course of disease are independent risk factors affecting prognosis. The distribution and features of drug susceptibility are as follows: ① G- bacteria were the most frequently isolated and the conditioned pathogen was mainly produced; ② The fungus was gradually isolated; ③ Drug resistance was high. Conclusion: It is the etiological and clinical features that lead to the high attack rate of ICU acquired septicemia.

Key words: Septicemia, Blood-borne pathogens, Custodial care

中图分类号: 

  • R378
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