山东大学学报 (医学版) ›› 2025, Vol. 63 ›› Issue (11): 98-104.doi: 10.6040/j.issn.1671-7554.0.2025.0145
• 公共卫生与预防医学 • 上一篇
孙淑凡1,钟毓2,赵琦1,曲一楠1,王骋3,王冬梅2
SUN Shufan1, ZHONG Yu2, ZHAO Qi1, QU Yinan1, WANG Cheng3, WANG Dongmei2
摘要: 目的 探讨山东省德州市冷季低温暴露与急救呼叫频次的关联,评估细颗粒物(fine particulate matter, PM2.5)及其组分对该关联的修饰效应,为应对不良大气环境的健康风险提供依据。 方法 收集德州市2020—2023年急救呼叫数据和同期气象数据,采用嵌套分布滞后非线性模型(distributed lag non-linear models, DLNM)的广义加性模型(generalized additive model, GAM)分析冷季(11月至次年2月)低温暴露与急救呼叫频次的关联程度,通过将PM2.5及组分与气温建立乘积项探究其修饰效应。 结果 2020—2023年冷季德州市总急救呼叫频次共150 408次。研究期间日平均温度(1.52±6.23)℃,PM2.5日平均质量浓度57.60±53.65 μg/m3。累积低温暴露与急救呼叫频次的关联曲线近似“U”型(滞后0~30 d),极端低温暴露(-6.03 ℃)和中度低温暴露(-1.02 ℃)对应的急救呼叫相对风险(relative risk, RR)及95%CI分别为1.61(1.36~1.91)和1.40(1.27~1.54)。在极端低温暴露时,黑碳和有机物可增加低温相关急救呼叫风险(P<0.05);在中度低温暴露时,PM2.5及组分可增加低温相关急救呼叫风险(P<0.01)。 结论 山东省德州市冷季低温暴露与急救呼叫频次增加显著相关,高浓度PM2.5及其组分可增强低温暴露-急救呼叫频次的关联强度。
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