山东大学学报 (医学版) ›› 2019, Vol. 57 ›› Issue (6): 33-39.doi: 10.6040/j.issn.1671-7554.0.2019.521
• • 上一篇
王国云,袁明,姬苗苗
WANG Guoyun, YUAN Ming, JI Miaomiao
摘要： 子宫内膜异位症(EMs)是妇科常见疾病,在育龄期妇女中发病率为10%,EMs的主要症状包括疼痛与不孕,严重影响患者生活质量。但是目前缺乏EMs特异性无创诊断方法,EMs的治疗方式主要限于手术治疗和激素治疗,且均存在不良反应较多、复发率较高的问题。EMs发病机制的不明确导致EMs诊疗尚无突破性进展。目前经血逆流学说为EMs发病主流学说,但最新研究表明EMs是一个复杂的慢性疾病,经血逆流很可能只是EMs的诱因,后续复杂的基因、免疫与环境因素之间的相互作用在EMs进程中发挥重要作用。归纳目前EMs主要发病机制学说,凝练EMs各分支领域的最新进展,着重总结EMs研究的新方向,并进一步提出EMs机制研究中面临的难题。
中图分类号:
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