山东大学学报 (医学版) ›› 2020, Vol. 58 ›› Issue (2): 44-48.doi: 10.6040/j.issn.1671-7554.0.2019.1334
张春云,何伟,姜彬,危兆胜,王志刚
ZHANG Chunyun, HE Wei, JIANG Bin, WEI Zhaosheng, WANG Zhigang
摘要: 目的 探讨神经导航辅助脑内血肿穿刺术对幕上高血压性脑出血合并脑疝征象的治疗效果及安全性。 方法 2015年7月至2018年12月选取山东大学齐鲁医院(青岛)符合纳入标准的33例患者,分成导航辅助微创穿刺组和传统开颅手术组进行血肿清除治疗,比较两组手术时间、血肿清除率及术后并发症发生率。采用格拉斯哥昏迷评分(GCS)对患者的术前及术后第1天神经功能缺损情况进行评估,Modified Rankin Scale(mRS)评分作为患者术后的随访量表,评估患者术后的神经功能康复情况。 结果 两组患者在基线比较上无差别,在手术持续时间方面,微创穿刺组明显短于开颅组(P<0.01),而开颅组血肿清除率高于微创穿刺组(P<0.01)。术后第1天GCS评分差异无统计学意义(P=0.29),6个月后mRS评分差异有统计学意义(P=0.026),在再出血及脑积水并发症发生率方面,两组差异无统计学意义。 结论 神经导航辅助脑内血肿穿刺治疗幕上合并脑疝征象的脑出血具有操作迅速、安全、神经功能恢复更佳等特点,可以改善患者的预后。
中图分类号:
[1] | Heros RC. Cerebellar hemorrhage and infarction [J]. Stroke, 1982, 13(1): 106-109. |
[2] | Arnone GD, Esfahani DR, Wonais M, et al. Surgery for cerebellar hemorrhage: a national surgical quality Improvement program database analysis of patient outcomes and factors associated with 30-day mortality and prolonged entilation [J]. World Neurosurg, 2017, 106543-106550. |
[3] | Broderick J, Connolly S, Feldmann E, et al. Guidelines for the management of spontaneous intracerebral hemorrhage in adults: 2007 update: a guideline from the American Heart Association/American Stroke Association Stroke Council, High Blood Pressure Research Council, and the Quality of Care and Outcomes in Research Interdisciplinary Working Group [J]. Stroke, 2007, 38(6): 2001-2023. |
[4] | Chartrain AG, Kellner CP, Fargen KM, et al. A review and comparison of three neuronavigation systems for minimally invasive intracerebral hemorrhage evacuation [J]. J Neurointerv Surg, 2018, 10(1): 66-74. |
[5] | Batjer HH, Reisch JS, Allen BC, et al. Failure of surgery to improve outcome in hypertensive putaminal hemorrhage. a prospective randomized trial [J]. Arch Neurol, 1990, 47(10):1103-1106. |
[6] | Juvela S, Heiskanen O, Poranen A,et al. The treatment of spontaneous intracerebral hemorrhage. a prospective randomized trial of surgical and conservative treatment [J]. J Neurosurg, 1989, 70(5):755-758. |
[7] | Mendelow AD, Gregson BA, Fernandes HM, et al. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage(STICH): a randomised trial [J]. Lancet, 2005, 365(9457): 387-397. |
[8] | Mendelow AD, Gregson BA, Rowan EN, et al. Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas(STICH II): a randomised trial [J]. Lancet, 2013, 382(9890): 397-408. |
[9] | Hadjiathanasiou A, Schuss P, Ilic I, et al. Decompressive craniectomy for intracerebral haematoma: the influence of additional haematoma evacuation [J]. Neurosurg Rev, 2018,41(2):649-654. |
[10] | Bhatia K, Hepburn M, Ziu E, et al. Modern approaches to evacuating intracerebral hemorrhage [J]. Curr Cardiol Rep, 2018, 20(12): 132. doi: 10.1007/s11886-018-1078-4. |
[11] | Fu C, Wang N, Chen B, et al. Surgical management of moderate basal ganglia intracerebral hemorrhage: comparison of safety and efficacy of endoscopic surgery,minimally invasive puncture and drainage, and craniotomy [J]. World Neurosurg, 2019, 122:e995-e1001. doi: 10.1016/j.wneu.2018.10.192. |
[12] | Hersh EH, Gologorsky Y, Chartrain AG, et al. Minimally invasive surgery for intracerebral hemorrhage [J]. Curr Neurol Neurosci Rep, 2018, 18(6): 34. |
[13] | Choo YS, Chung J, Joo JY, et al. Borderline basal ganglia hemorrhage volume: patient selection for good clinical outcome after stereotactic catheter drainage [J]. J Neurosurg, 2016, 125(5): 1242-1248. |
[14] | Prasad K, Mendelow AD, Gregson B. Surgery for primary supratentorial intracerebral haemorrhage[J]. Cochrane Database Syst Rev, 2008, 4: Cd000200. doi: 10.1002/14651858.CD000200. |
[15] | Awad IA, Polster SP, Carrion-Penagos J, et al. Surgical performance determines functional outcome benefit in the minimally invasive surgery plus recombinant tissue plasminogen activator for intracerebral hemorrhage evacuation(MISTIE)procedure [J]. Neurosurgery, 2019, 84(6): 1157-1168. |
[16] | Li Y, Yang R, Li Z, et al. Surgical evacuation of spontaneous supratentorial lobar intracerebral hemorrhage: comparison of safety and efficacy of stereotactic aspiration, endoscopic surgery, and craniotomy [J]. World Neurosurgery, 2017, 105:332-340. doi: 10.1016/j.wneu. 2017.05.134. |
[17] | 陈俊瑜, 胡飞, 岑波, 等. 神经导航引导下硬通道多靶点穿刺引流治疗高血压脑出血48例疗效分析[J]. 华中科技大学学报(医学版), 2017, 46(1):72-75. CHEN Junyu, HU Fei, CEN Bo, et al. Clinical analysis of treatment of 48 cases with hypertensive cerebral hemorrhage by hypertensive cerebral hemorrhage by flinty channel multi-target puncture and drainage guided by neural navigation [J]. Acta Medicinae Universitatis Scientiae et Technologiae Huazhong, 2017, 46(1):72-75. |
[18] | Ge C, Zhao W, Guo H, et al. Comparison of the clinical efficacy of craniotomy and craniopuncture therapy for the early stage of moderate volume spontaneous intracerebral haemorrhage in basal ganglia: using the CTA spot sign as an entry criterion [J]. Clin Neurol Neurosurg, 2018, 169:41-48. doi: 10.1016/j.clineuro.2018.04.002. |
[19] | Eroglu U, Kahilogullari G, Dogan I, et al. Surgical management of supratentorial intracerebral hemorrhages: endoscopic versus open surgery [J]. World Neurosurgery, 2018, 114e60-e65. doi: 10.1016/j.wneu.2018.02.056. |
[20] | Wang T, Guan Y, Du J, et al. Factors affecting the evacuation rate of intracerebral hemorrhage in basal ganglia treated by minimally invasive craniopuncture [J]. Clin Neurol Neurosurg, 2015, 134:104-109. doi: 10.1016/j.clineuro.2015.04.020. |
[21] | Algattas H, Kimmell KT, Vates GE. Risk of reoperation for hemorrhage in patients after craniotomy [J]. World Neurosurgery, 2016, 87:531-539. doi:10.1016/j.wneu.2015.09.020. |
[22] | Winkler EA, Minter D, Yue JK, et al. Cerebral edema in traumatic brain injury: pathophysiology and prospective therapeutic targets[J]. Neurosurgery Clinics of North America, 2016, 27(4): 473-488. |
[23] | Bareyre F, Wahl F, McIntosh TK, et al. Time course of cerebral edema after traumatic brain injury in rats: effects of riluzole and mannitol [J]. Journal of Neurotrauma, 1997, 14(11): 839-849. |
[24] | Kuo LT, Chen CM, Li CH, et al. Early endoscope-assisted hematoma evacuation in patients with supratentorial intracerebral hemorrhage: case selection, surgical technique, and long-term results [J]. Neurosurg Focus, 2011, 30(4): E9. doi:10.3171/2011.2.FOCUS10313. |
[25] | Liu LJ, Xue ZC, Yang GQ, et al. Optimal time window for minimally invasive aspiration and drainage of the hematoma in patients with intracerebral hemorrhage [J]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue, 2004, 16(9): 544-546. |
[1] | 郑苏,陈述花,李华,邓劼,陈春红,王晓慧,冯卫星,韩萧迪,张雨佳,李娜,李莫,方方. 脑电变化和BASED评分与54例婴儿痉挛症促肾上腺皮质激素疗效的相关性[J]. 山东大学学报 (医学版), 2022, 60(9): 91-96. |
[2] | 王丽慧,高敏,孔北华. 子宫血管肉瘤2例报告并文献复习[J]. 山东大学学报 (医学版), 2022, 60(9): 108-112. |
[3] | 高中霞,张铭,樊明德,谭晨阳,王梦迪,王超,樊跃飞,丁守銮,王成伟. 伽玛刀治疗81例肺癌脑转移瘤的疗效及预后因素[J]. 山东大学学报 (医学版), 2022, 60(8): 44-49. |
[4] | 贺士卿,李皖皖,董书晴,牟婧怡,刘宇莹,魏思雨,刘钊,张家新. 基于数据库构建乳腺癌焦亡相关基因的预后风险模型[J]. 山东大学学报 (医学版), 2022, 60(8): 34-43. |
[5] | 张玉凤,徐敏,邢秀丽,逄曙光,户克庆. 689例非ST段抬高型心肌梗死患者的临床流行病学特征[J]. 山东大学学报 (医学版), 2022, 60(7): 118-122. |
[6] | 李琳琳,王凯. 基于生物信息学预测肝细胞癌预后基因[J]. 山东大学学报 (医学版), 2022, 60(5): 50-58. |
[7] | 郑昊天,王光辉,赵小刚,王亚东,曾榆凯,杜贾军. 基于数据库LKB1突变肺腺癌DNA异常甲基化位点构建的预后风险模型[J]. 山东大学学报 (医学版), 2022, 60(3): 51-58. |
[8] | 陈立晓,英信江,陈歆维,王菲,孙臻峰,董频. 下咽鳞癌蛋白质谱鉴定及预后靶分子筛选[J]. 山东大学学报 (医学版), 2021, 59(9): 140-147. |
[9] | 褚晏,刘端瑞,朱文帅,樊荣,马晓丽,汪运山,郏雁飞. DNA甲基化转移酶在胃癌中的表达及其临床意义[J]. 山东大学学报 (医学版), 2021, 59(7): 1-9. |
[10] | 陈丽宇,肖娟,吕仙忠,段宝敏,洪凡真. 影响孕产妇下肢深静脉血栓预后的危险因素分析[J]. 山东大学学报 (医学版), 2021, 59(7): 38-42. |
[11] | 田瑶天,王宝,李叶琴,王滕,田力文,韩波,王翠艳. 基于可解释性心脏磁共振参数的机器学习模型预测儿童心肌炎的预后[J]. 山东大学学报 (医学版), 2021, 59(7): 43-49. |
[12] | 李皖皖,周文凯,董书晴,贺士卿,刘钊,张家新,刘斌. 利用数据库信息构建乳腺癌免疫关联lncRNAs风险评估模型[J]. 山东大学学报 (医学版), 2021, 59(7): 74-84. |
[13] | 米琦,史爽,李娟,李培龙,杜鲁涛,王传新. 膀胱癌circRNAs介导的ceRNA网络及预后评估模型的构建[J]. 山东大学学报 (医学版), 2021, 59(6): 94-102. |
[14] | 谢同辉,陈志强,常建华,赵丹文,徐博文,智绪亭. 肝内胆管癌根治性切除术后生存因素分析及列线图的建立[J]. 山东大学学报 (医学版), 2021, 59(4): 93-99. |
[15] | 李湘青,殷欣,赵雪莲,赵培庆. NK细胞亚群CD56bright在帕金森患者外周血中的表达及临床意义[J]. 山东大学学报 (医学版), 2021, 59(2): 34-40. |
|