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山东大学学报 (医学版) ›› 2020, Vol. 58 ›› Issue (2): 49-53.doi: 10.6040/j.issn.1671-7554.0.2019.1381

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聚乙二醇电解质散在40例妇科腹腔镜术前肠道准备中的应用

张召义1,韩婷2,孙艳萍1,李波1   

  1. 山东大学附属生殖医院 山东大学生殖医学研究中心 国家辅助生殖与优生工程技术研究中心 生殖内分泌教育部重点实验室 1.麻醉科;2. 妇科, 山东 济南 250001
  • 出版日期:2020-02-10 发布日期:2022-09-27
  • 通讯作者: 韩婷. E-mail:hantingzhao@163.com
  • 基金资助:
    国家自然科学基金青年科学基金(81701406);山东省医药卫生科技发展计划(201401)

Application of polyethylene glycol electrolyte powder in intestinal preparation of 40 cases before gynecological laparoscopic operation

ZHANG Zhaoyi1, HAN Ting2, SUN Yanping1, LI Bo1   

  1. 1. Department of Anesthesiology;
    2. Department of Gynecology, Reproductive Hospital Affiliated to Shandong University;
    Center for Reproductive Medicine, Shandong University;
    National Research Center for Assisted Reproductive Technology and Reproductive Genetics, China;
    The Key laboratory for Reproductive Endocrinology of Ministry of Education, Jinan 250001, Shandong, China
  • Online:2020-02-10 Published:2022-09-27

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摘要： 目的 探讨聚乙二醇电解质散(PGEP)在妇科腹腔镜术前肠道准备中的应用效果。 方法 选取2019年2月至2019年5月行妇科腹腔镜手术的患者80例,采用随机数字表法分为两组(研究组和对照组各40例)。研究组采用肥皂水灌肠联合口服PGEP溶液进行术前肠道准备,对照组采用肥皂水灌肠进行肠道准备,比较两组患者术前血指标及肠道准备的效果。 结果 两组患者术前血钾、血钠、血红蛋白、红细胞压积、血pH值、低钠血症/低钾血症发生率、术后排气时间及手术医师对患者的肠道准备满意度差异均无统计学意义(P>0.05),两组患者均未发生重度低钠血症、低钾血症或严重并发症;研究组患者血糖［4.90(4.70, 5.28)mmol/L vs 5.25(4.83, 5.70)mmol/L, z=-2.30, P=0.02］和手术时间［35.00(25.00, 50.00)min vs 57.50(41.25, 90.00)min, z=-4.01, P<0.001］均低于对照组。 结论 口服PGEP对妇科腹腔镜术前血钾、血钠、血红蛋白、红细胞压积、血pH值无影响,且能够提高肥皂水肠道准备效果,不影响术后肠蠕动恢复。

关键词: 聚乙二醇电解质散, 肠道准备, 血气分析, 妇科, 腹腔镜

Abstract: Objective To investigate the application of polyethylene glycol electrolyte powder(PGEP)in intestinal preparation before gynecological laparoscopic surgery. Methods A total of 80 patients undergoing laparoscopic gynecological surgery during Feb. 2019 and May 2019 were randomly divided into two groups. The study group used soap water enema combined with oral PGEP solution for intestinal preparation before operation, while the control group used soap water enema for intestinal preparation. The blood indexes and intestinal preparation effects of the two groups were compared. Results There were no significant differences between the two groups in blood potassium, blood sodium, hemoglobin, hematocrit, pH value, incidence of hyponatremia/hypokalemia, exhaust time after operation and satisfaction of surgeons with intestinal preparation(P>0.05). No severe hyponatremia, hypokalemia or serious complications occurred. Blood glucose was 4.90(4.70, 5.28)mmol/L in the study group and 5.25(4.83, 5.70)mmol/L in the con- 山 东 大 学 学 报 (医 学 版)58卷2期 -张召义,等.聚乙二醇电解质散在40例妇科腹腔镜术前肠道准备中的应用 \=-trol group(z=-2.30, P=0.02), and operation time was 35.00(25.00, 50.00)min in the study group and 57.50(41.25, 90.00)min in the control group(z=-4.01, P<0.001). Conclusion PGEP does not affect blood potassium, blood sodium, hemoglobin, hematocrit and blood pH before gynecological laparoscopic operation. It can improve the intestinal preparation results of soapy water without affecting the recovery of intestinal peristalsis.

Key words: Polyethylene glycol electrolyte powder, Intestinal preparation, Blood gas analysis, Gynecology, Laparoscopy

中图分类号: 

  • R614
[1] 胡三元. 经脐单孔腹腔镜手术的再认识[J]. 山东大学学报(医学版), 2019, 57(12): 1-4. HU Sanyuan. Rethinking about laparoendoscopic single-site surgery[J]. Journal of Shandong University(Health Sciences), 2019, 57(12): 1-4.
[2] Moolla M, Dang JT, Shaw A, et al. Simethicone decreases bloating and improves bowel preparation effectiveness: a systematic review and meta-analysis[J]. Surg Endosc, 2019, 33(12): 3899-3909.
[3] Castro FJ, Al-Khairi B, Singh H, et al. Randomized controlled trial: split-dose and same-day sarge volume bowel preparation for afternoon colonoscopy have similar quality of preparation[J]. J Clin Gastroenterol, 2019, 53(10): 724-730.
[4] Chinese guideline for bowel preparation for colonoscopy(2019, Shanghai)[J]. Zhonghua Nei Ke Za Zhi, 2019, 58(7): 485-495.
[5] Hassan C, East J, Radaelli F, et al. Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy(ESGE)Guideline—Update 2019[J]. Endoscopy, 2019, 51(8): 775-794.
[6] Anderson J, Furnival RA, Zhang L, et al. A comparison of the efficacy of enema solutions in pediatric emergency department patients[J]. J Emerg Med, 2019, 57(4): 461-468.
[7] Li CX, Guo Y, Zhu YJ, et al. Comparison of polyethylene glycol versus lactulose oral solution for bowel preparation prior to colonoscopy[J]. Gastroenterol Res Pract, 2019, 2019: 2651450. doi: 10.1155/2019/2651450.
[8] Mangira D, Ket S, Dwyer J, et al. Augmentation with pre-emptive macrogol-based osmotic laxative does not significantly improve standard bowel preparation in unselected patients: a randomized trial[J]. JGH Open, 2019, 3(5): 374-380.
[9] McChesney SL, Zelhart MD, Green RL, et al. Current U.S. pre-operative bowel preparation trends: a 2018 survey of the American society of colon and rectal surgeons members[J]. Surg Infect(Larchmt), 2019. doi: 10.1089/sur.2019.125.
[10] Yi LJ, Tian X, Shi B, et al. Low-volume polyethylene glycol improved patient attendance in bowel preparation before colonoscopy: a meta-analysis with trial sequential analysis[J]. Front Med(Lausanne), 2019, 6: 92. doi: 10.3389/fmed.2019.00092.
[11] Castro FJ, Al-Khairi B, Singh H, et al. Randomized controlled trial: split-dose and same-day large volume bowel preparation for afternoon colonoscopy have similar quality of preparation[J]. J Clin Gastroenterol, 2019, 53(10): 724-730.
[12] Sriphongphankul H, Tanpowpong P, Lertudomphonwanit C, et al. Split dose versus full single-dose regimen of polyethylene glycol for bowel preparation in pediatric colonoscopy: a pilot study of randomized controlled trial[J]. Eur J Gastroenterol Hepatol, 2019, 31(11): 1382-1386.
[13] Gkolfakis P, Tziatzios G, Papanikolaou IS, et al. Strategies to improve inpatients quality of bowel preparation for colonoscopy: a systematic review and meta-analysis[J]. Gastroenterol Res Pract, 2019, 2019: 5147208. doi: 10.1155/2019/5147208.
[14] Argyropoulos SK, Mahmood SK, Campbell EJ, et al. Improving the quality of inpatient bowel preparation for colonoscopies[J]. Dig Dis Sci, 2018, 63(2): 338-344.
[15] Yang HJ, Park DI, Park SK, et al. A randomized controlled trial comparing colonoscopic enema with additional oral preparation as a salvage for inadequate bowel cleansing before colonoscopy[J]. J Clin Gastroenterol, 2019, 53(8): e308-e315.
[16] Lewis J, Kinross J. Mechanical bowel preparation for elective colorectal surgery[J]. Tech Coloproctol, 2019, 23(8): 783-785.
[17] Deng H, Liu YY, Tan C, et al. A randomized single blind comparison of conventional bowel preparation and unplanned preoperative preparation for pelvic organ prolapse[J]. Zhonghua Fu Chan Ke Za Zhi, 2019, 54(2): 97-102.
[18] Ryan NA, Ng VS, Sangi-Haghpeykar H,et al. Evaluating mechanical bowel preparation prior to total laparoscopic hysterectomy[J]. JSLS, 2015, 19(3). doi: 10.4293/JSLS.2015.00035.
[19] Sanguandeekul N, Vallibhakara O, Arj-Ong Vallibhakara S, et al. Gastrointestinal injuries during gynaecologic operations at a university teaching hospital in Thailand: a 10-year review[J]. J Obstet Gynaecol, 2019, 39(3): 384-388.
[20] Peri A. Management of hyponatremia: causes, clinical aspects, differential diagnosis and treatment[J]. Expert Rev Endocrinol Metab, 2019, 14(1): 13-21.
[21] Francesco T, Giovambattista C, Robert U. Electrolytes and acid—base: common fluid and electrolyte disorders[J]. Medicine, 2019, 47(8): 489-497.
[22] Anderson J, Furnival RA, Zhang L, et al. A comparison of the efficacy of enema solutions in pediatric emergency department patients[J]. J Emerg Med, 2019, 57(4): 461-468.
[23] Costelha J, Dias R, Teixeira C, et al. Hyponatremic coma after bowel preparation[J]. Eur J Case Rep Intern Med, 2019, 6(9): 001217. doi: 10.12890/2019_001217.
[24] Llerena E, Varea Calderón V, Pujol Muncunill G, et al. Comparison of the effectiveness and safety of polyethylene glycol with and without electrolytes in the treatment of chronic constipation[J]. An Pediatr(Barc), 2016, 85(1): 34-40.
[25] Wang K, Zhang N, Deng D, et al. Clinical analysis of perioperative electrolyte imbalance in 999 patients undergoing gastrointestinal surgery[J]. Zhonghua Wei Chang Wai Ke Za Zhi, 2018, 21(12): 1427-1432.
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