山东大学学报（医学版） ›› 2014, Vol. 52 ›› Issue (11): 65-67.doi: 10.6040/j.issn.1671-7554.0.2014.336
焦瑾, 王茂水, 吴艳华, 王新锋
JIAO Jin, WANG Maoshui, WU Yanhua, WANG Xinfeng
摘要： 目的 探讨ALS试验(TB-SA抗体)在结核性胸膜炎辅助诊断中的应用价值.方法 选取初治结核性胸膜炎患者(结核组)55例和健康体检者(对照组)45例,采用ELISA法测定淋巴细胞分泌液中结核抗体的含量.采用Mann-Whitney U检验比较两组之间TB-SA抗体的差异,绘制受试者工作特征(ROC)曲线评价ALS试验(TB-SA抗体)对结核性胸膜炎诊断的敏感性.结果 结核组TB-SA抗体的浓度显著高于正常组(P<0.01). 根据两组数据绘制受试者工作特征曲线(ROC曲线),曲线下面积为0.900(95%CI:0.824～0.951),截断点为0.04,敏感性和特异性分别为77.8%和92.7%,阳性似然比和阴性似然比分别为10.69和0.24.结论 ALS(TB-SA抗体)试验在结核性胸膜炎的诊断中具有一定的价值.
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