Journal of Shandong University (Health Sciences) ›› 2019, Vol. 57 ›› Issue (10): 1-6.doi: 10.6040/j.issn.1671-7554.0.2019.726

   

Progress in assisted reproductive technology

SHI Juanzi, CHEN Lijuan   

  1. The Assisted Reproduction Center, Northwest Women and Childrens Hospital of Xian Jiaotong University, Xian 710000, Shaanxi, China
  • Published:2022-09-27

PDF (PC)

29

Abstract: Human assisted reproductive technology(ART)has made much progress and acted as the most effective 山 东 大 学 学 报 (医 学 版)57卷10期 -师娟子,等.辅助生殖技术进展 \=-treatment for infertility. It has also been applied to block genetic diseases and preserve fertility. In the advances of ART, studies exploring genetics of gametes and embryos, embryo transfer strategy and fertility preservation have emerged in large numbers in recent years and a series of results have been published. In the future, ART is likely to be used in gene therapy of gametes and embryos, stem cells, and so on. These new technologies will bring serious challenges to safety, ethics and society, which need to be tackled with interdisciplinary efforts.

Key words: Assisted reproductive technology, Preimplantation genetic testing, Gamete quality, Fertility preservation, Gene therapy

CLC Number: 

  • R711.6
[1] 卢光秀. 辅助生育技术进展──人工授精技术进展[J]. 中国实用妇科与产科杂志, 2001, 17(1): 14-15.
[2] Helmerhorst FM, Perquin DAM, Donker D, et al. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies [J]. BMJ, 2004, 328(7434): 261.
[3] Catford SR, Mclachlan RI, OBryan MK, et al. Long-term follow-up of ICSI-conceived offspring compared with spontaneously conceived offspring: a systematic review of health outcomes beyond the neonatal period [J]. Andrology, 2018, 6(5): 635-653.
[4] Mukaida T. Vitrification of human embryos based on the assessment of suitable conditions for 8-cell mouse embryos [J]. Hum Reprod, 1998, 13(10): 2874-2879.
[5] Harper JC, Schatten G. Are we ready for genome editing in human embryos for clinical purposes? [J]. Eur J Med Genet, 2019, 62(8): 103682.
[6] Lambalk CB, Banga FR, Huirne JA, et al. GnRH antagonist versus long agonist protocols in IVF: a systematic review and meta-analysis accounting for patient type [J]. Hum Reprod Update, 2017, 23(5): 560-579.
[7] Wei D, Sun Y, Liu J, et al. Live birth after fresh versus frozen single blastocyst transfer(Frefro-blastocyst): study protocol for a randomized controlled trial [J]. Trials, 2017, 18(1): 253.
[8] Shi Y, Sun Y, Hao C, et al. Transfer of Fresh versus Frozen Embryos in Ovulatory Women [J]. N Engl J Med, 2018, 378(2): 126-136.
[9] Rienzi L, Gracia C, Maggiulli R, et al. Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance [J]. Hum Reprod Update, 2017, 23(2): 139-155.
[10] Wang S, Chen L, Fang J, et al. Comparison of the pregnancy and obstetric outcomes between single cleavage-stage embryo transfer and single blastocyst transfer by time-lapse selection of embryos [J]. Gynecol Endocrinol, 2019, 11: 1-4.
[11] Handyside AH, Kontogianni EH, Hardy K, et al. Pregnancies from biopsied human preimplantation embryos sexed by Y-specific DNA amplification [J]. Nature, 1990, 344(6268): 768-770.
[12] Feng R, Sang Q, Kuang Y, et al. Mutations in TUBB8 and Human Oocyte Meiotic Arrest [J]. N Engl J Med, 2016, 374(3): 223-232.
[13] Sang Q, Zhang Z, Shi J, et al. A pannexin 1 channelopathy causes human oocyte death [J]. Sci Transl Med, 2019, 11(485): eaav8731.
[14] Sang Q, Li B, Kuang Y, et al. Homozygous mutations in WEE2 cause fertilization failure and female infertility [J]. Am J Hum Genet, 2018, 102(4): 649-657.
[15] Mu J, Wang W, Chen B, et al. Mutations in NLRP2 and NLRP5 cause female infertility characterised by early embryonic arrest [J]. J Med Genet, 2019, 56(7):471-480.
[16] Xu Y, Shi Y, Fu J, et al. Mutations in PADI6 cause female infertility characterized by early embryonic arrest [J]. Am J Hum Genet, 2016, 99(3): 744-752.
[17] Yang P, Luan X, Peng Y, et al. Novel zona pellucida gene variants identified in patients with oocyte anomalies [J]. Fertil Steril, 2017, 107(6): 1364-1369.
[18] Chen B, Zhang Z, Sun X, et al. Biallelic mutations in PATL2 cause female infertility characterized by oocyte maturation arrest [J]. Am J Hum Genet, 2017, 101(4): 609-615.
[19] Thirumavalavan N, Gabrielsen JS, Lamb DJ. Where are we going with gene screening for male infertility? [J]. Fertil Steril, 2019, 111(5): 842-850.
[20] Laan M. Systematic review of the monogenetic causes of male infertility: the first step towards diagnostic gene panels in the andrology clinic [J]. Hum Reprod, 2019, 34(5): 783-785.
[21] Gershoni M, Hauser R, Barda S, et al. A new MEIOB mutation is a recurrent cause for azoospermia and testicular meiotic arrest [J]. Hum Reprod, 2019, 34(4): 666-671.
[22] Ma Y, Xie N, Xie D, et al. A novel homozygous FBXO43 mutation associated with male infertility and teratozoospermia in a consanguineous Chinese family [J]. Fertil Steril, 2019, 111(5): 909-917.
[23] Chen ZJ, Shi Y, Sun Y, et al. Fresh versus frozen embryos for infertility in the polycystic ovary syndrome [J]. N Engl J Med, 2016, 375(6): 523-533.
[24] Wu Y, Chen W, Zhou L, et al. Single embryo transfer improve the perinatal outcome in singleton pregnancy [J]. J Matern Fetal Neonatal Med, 2019, 27:1-6. doi:10.1080/14767058.2019.
[25] Assou S, Aït-Ahmed O, El Messaoudi S, et al. Non-invasive pre-implantation genetic diagnosis of X-linked disorders [J]. Med Hypotheses, 2014, 83(4): 506-508.
[26] Wu H, Ding C, Shen X, et al. Medium-based noninvasive preimplantation genetic diagnosis for human α-thalassemias-SEA [J]. Medicine, 2015, 94(12): e669.
[27] Xu J, Fang R, Chen L, et al. Noninvasive chromosome screening of human embryos by genome sequencing of embryo culture medium for in vitro fertilization [J]. Proc Natl Acad Sci U S A, 2016, 113(42): 11907-11912.
[28] Gómez-Tatay L, Hernández-Andreu JM, Aznar J. Mitochondrial modification techniques and ethical issues [J]. J Clin Med, 2017, 6(3): 1-16.
[29] Toyooka Y, Tsunekawa N, Akasu R, et al. Embryonic stem cells can form germ cells in vitro[J]. Proc Natl Acad Sci U S A, 2003, 100(20): 11457-11462.
[30] Hübner K, Fuhrmann G, Christenson LK, et al. Derivation of oocytes from mouse embryonic stem cells [J]. Science, 2003, 300(5623): 1251-1256.
[31] Thomas CD, Cameron A, Green RE, et al. Extinction risk from climate change [J]. Nature, 2004, 427(6970): 145-148.
[32] Tan J, Kan A, Hitkari J, et al. The role of the endometrial receptivity array(ERA)in patients who have failed euploid embryo transfers [J]. J Assist Reprod Genet, 2018, 35(4): 683-692.
[33] Bassil R, Casper R, Samara N, et al. Does the endometrial receptivity array really provide personalized embryo transfer? [J]. J Assist Reprod Genet, 2018, 35(7): 1301-1305.
[34] Peccatori FA, Azim HA Jr, Orecchia R, et al. Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up [J]. Ann Oncol, 2013, 24(Suppl 6): vi160-170.
[35] Donnez J, Dolmans MM, Demylle D, et al. Livebirth after orthotopic transplantation of cryopreserved ovarian tissue [J]. Lancet, 2004, 364(9443): 1405-1410.
[36] Donnez J, Dolmans MM, Pellicer A, et al. Restoration of ovarian activity and pregnancy after transplantation of cryopreserved ovarian tissue: a review of 60 cases of reimplantation [J]. Fertil Steril, 2013, 99(6): 1503-1513.
[37] Donnez J, Dolmans MM. Fertility preservation in women [J]. N Engl J Med, 2017, 377(17): 1657-1665.
[38] Roque M, Sampaio M, Salles PG, et al. Onco-testicular sperm extraction: birth of a healthy baby after fertility preservation in synchronous bilateral testicular cancer and azoospermia [J]. Andrologia, 2015, 47(4): 482-485.
[39] 李定明,蒋敏. 睾丸肿瘤患者的生育力保存[J]. 实用医院临床杂志, 2018, 15(4): 257-259.
[1] ZHANG Shi-Bao, LIU Qing-Yong, RUAN Xi-Yun, CHEN Jie, ZHANG Jian-Jun, LI Zong-Wu, YANG Guang-Xiao, WANG Quan-Ying. onstruction and identification of the expression vector of
NT4-SAC-HA2-TAT fusion gene [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2209, 47(6): 15-19.
[2] RUAN Xiangyan, CHENG Jiaojiao, DU Juan, GU Muqing. Ovarian tissue cryopreservation and preservation [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 24-30.
[3] WU Ruifang, LI Changzhong. Status and progress of female fertility protection [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 1-7.
[4] SHI Yuhua, PAN Ye, XIE Yanqiu. Latest advances of embryo cryopreservation technology [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 12-18.
[5] YAN Lei, YUE Caixin, LIU Yichun. Fertility preservation in patients with endometriosis [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 31-34.
[6] LU Qun, ZHAO Lulu. Progress on assisted reproductive technology for women with atypical endometrial hyperplasia and endometrial carcinoma receiving fertilitysparing treatment [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 35-41.
[7] LIN Yun, XIE Yanqiu. Fertility protection and preservation in breast cancer patients [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 42-46.
[8] HAO Guimin, LUO Zhuoye, WANG Yizhuo. Ethical issues and considerations in fertility preservation [J]. Journal of Shandong University (Health Sciences), 2022, 60(9): 47-52.
[9] Yuhua SHI,Qiumin WANG,Dan QI. Frontier research hotspot and progress in assisted reproductive technology [J]. Journal of Shandong University (Health Sciences), 2021, 59(9): 97-102.
[10] ZHAO Bingqing, GAO Xuan, LI Jiangxia. A retrospective analysis of chromosome karyotypes in RSA couples from assisted reproductive population [J]. Journal of Shandong University (Health Sciences), 2021, 59(7): 26-31.
[11] ZHU Xuli, ZHOU Liang, WANG Yue, SUN Qingyun, CAO Mingya, DU Yuanjie, CAO Jinfeng, ZHAO Zhiming, HAO Guimin. Correlation analysis of freezing methods with different sperm sources and pregnancy outcomes [J]. Journal of Shandong University (Health Sciences), 2021, 59(6): 86-93.
[12] CAO Mingya, ZHAO Hanjie, FENG Tengfei, JIA Rui, ZHAO Zhiming, HAO Guimin. Effect of fetal reduction in early pregnancy on perinatal mothers and infants after embryo transfer [J]. Journal of Shandong University (Health Sciences), 2020, 58(11): 65-70.
[13] RUAN Xiangyan, CHENG Jiaojiao, DU Juan, LI Yanglu, JIN Fengyu, Alfred O. MUECK. Research progress of fertility preservation methods [J]. Journal of Shandong University (Health Sciences), 2019, 57(2): 29-34.
[14] CAO Dongyan, BI Xiaoning, SHEN Keng. Application of anti-Mullerian hormone in gynecologic oncology [J]. Journal of Shandong University (Health Sciences), 2018, 56(5): 8-12.
[15] ZHOU Huimei, YANG Jiaxin, CAO Dongyan, SHEN Keng, XIANG Yang, WU Ming, PAN Lingya, HUANG Huifang, LANG Jinghe. Fertility-sparing radical trachelectomy for young women with early stage cervical cancer: surgical and obstetrical outcomes [J]. Journal of Shandong University (Health Sciences), 2018, 56(5): 18-22.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
No Suggested Reading articles found!
Copyright 2018 © Editorial office of Journal of Shandong University (Health Sciences)
Supported by Beijing Magtech Co.Ltd