Journal of Shandong University (Health Sciences) ›› 2022, Vol. 60 ›› Issue (9): 19-23.doi: 10.6040/j.issn.1671-7554.0.2022.0874

Previous Articles     Next Articles

Status and progress of oocyte cryopreservation

MA Xiang, ZHAO Feiyan   

  1. State Key Laboratory of Reproductive Medicine, Center of Clinical Reproductive Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu, China
  • Published:2022-09-02

Abstract: Oocyte cryopreservation has a history of more than 30 years, which is mainly applicable to the fertility preservation of cancer patients before radiotherapy and chemotherapy, or non-cancer patients and people who delay childbearing due to personal factors. In addition, it can also be used as a remedy for male inability to provide sperm due to special factors in the process of assisted reproduction. At present, the commonly used methods of oocyte cryopreservation include slow cryopreservation and vitrification cryopreservation, and with the progress of research, vitrification has gradually replaced slow cryopreservation. Many studies have shown no significant differences in clinical pregnancy rates, obstetric and perinatal outcomes between embryos transferred using frozen eggs and fresh eggs.

Key words: Egg freezing, Clinical application, Oocyte cryopreservation, Effectiveness, Safety

CLC Number: 

  • R711.6
[1] Chen C. Pregnancy after human oocyte cryopreservation[J]. Lancet, 1986, 1(8486): 884-886.
[2] Kuleshova L, Gianaroli L, Magli C, et al. Birth following vitrification of a small number of human oocytes: case Report[J]. Hum Reprod, 1999, 14(12): 3077-3079.
[3] Benagiano G, Gianaroli L. The new Italian IVF legislation[J]. Reprod Biomed Online, 2004, 9(2): 117-125.
[4] Practice Committees of the American Society for Reproductive Medicine and the Society for Assisted Reproductive Technology. Mature oocyte cryopreservation: a guideline[J]. Fertil Steril, 2013, 99(1): 37-43.
[5] Kazem R, Thompson LA, Srikantharajah A, et al. Cryopreservation of human oocytes and fertilization by two techniques: in-vitro fertilization and intracytoplasmic sperm injection[J]. Hum Reprod, 1995, 10(10): 2650-2654.
[6] Donnez J, Dolmans MM. Fertility preservation in women[J]. N Engl J Med, 2017, 377(17): 1657-1665.
[7] Diaz-Garcia C, Domingo J, Garcia-Velasco JA, et al. Oocyte vitrification versus ovarian cortex transplantation in fertility preservation for adult women undergoing gonadotoxic treatments: a prospective cohort study[J]. Fertil Steril, 2018, 109(3): 478-485.
[8] Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics, 2021[J]. CA Cancer J Clin, 2021, 71(1): 7-33.
[9] Rodriguez-Wallberg KA, Oktay K. Fertility preservation during cancer treatment: clinical guidelines[J]. Cancer Manag Res, 2014, 6: 105-117. doi:10.2147/cmar.s32380.
[10] 中华人民共和国卫生部. 人类辅助生殖技术规范[J]. 中国生育健康杂志, 2004, 15(1): 4-9.
[11] Cobo A, Meseguer M, Remohí J, et al. Use of cryo-banked oocytes in an Ovum donation programme: a prospective, randomized, controlled, clinical trial[J]. Hum Reprod, 2010, 25(9): 2239-2246.
[12] Milán M, Cobo AC, Rodrigo L, et al. Redefining advanced maternal age as an indication for preimplantation genetic screening[J]. Reprod Biomed Online, 2010, 21(5): 649-657.
[13] Chamayou S, Sicali M, Alecci C, et al. The accumulation of vitrified oocytes is a strategy to increase the number of euploid available blastocysts for transfer after preimplantation genetic testing[J]. J Assist Reprod Genet, 2017, 34(4): 479-486.
[14] 肖亚玲, 孙正怡. 卵子的冷冻和复苏[J]. 实用妇产科杂志, 2016, 32(4): 248-250.
[15] Saragusty J, Arav A. Current progress in oocyte and embryo cryopreservation by slow freezing and vitrification[J]. Reproduction, 2011, 141(1): 1-19.
[16] Cobo A, Bellver J, de los Santos MJ, et al. Viral screening of spent culture media and liquid nitrogen samples of oocytes and embryos from hepatitis B, hepatitis C, and human immunodeficiency virus chronically infected women undergoing in vitro fertilization cycles[J]. Fertil Steril, 2012, 97(1): 74-78.
[17] Glujovsky D, Riestra B, Sueldo C, et al. Vitrification versus slow freezing for women undergoing oocyte cryopreservation[J]. Cochrane Database Syst Rev, 2014(9): CD010047. doi: 10.1002/14651858.
[18] Smith GD, Serafini PC, Fioravanti J, et al. Prospective randomized comparison of human oocyte cryopreservation with slow-rate freezing or vitrification[J]. Fertil Steril, 2010, 94(6): 2088-2095.
[19] Levi-Setti PE, Borini A, Patrizio P, et al. ART results with frozen oocytes: data from the Italian ART registry(2005-2013)[J]. J Assist Reprod Genet, 2016, 33(1): 123-128.
[20] Leung AQ, Baker K, Vaughan D, et al. Clinical outcomes and utilization from over a decade of planned oocyte cryopreservation[J].Reprod Biomed Online, 2021, 43(4): 671-679.
[21] Blakemore JK, Grifo JA, DeVore SM, et al. Planned oocyte cryopreservation-10-15-year follow-up: return rates and cycle outcomes[J]. Fertil Steril, 2021, 115(6): 1511-1520.
[22] Gurbuz A, Cil AP, Karakis LS, et al. Decision regret and associated factors following oocyte cryopreservation in patients with diminished ovarian reserve and/or age-related fertility decline[J]. J Assist Reprod Genet, 2021, 38(6): 1469-1479.
[23] Johnston M, Fuscaldo G, Richings NM, et al. Cracked open: exploring attitudes on access to egg freezing[J]. Sex Reprod Health Matters, 2020, 28(1): 1758441.
[24] Platts S, Trigg B, Bracewell-Milnes T, et al. Exploring womens attitudes, knowledge, and intentions to use oocyte freezing for non-medical reasons: a systematic review[J]. Acta Obstet Gynecol Scand, 2021, 100(3): 383-393.
[25] Forman EJ, Li X, Ferry KM, et al. Oocyte vitrification does not increase the risk of embryonic aneuploidy or diminish the implantation potential of blastocysts created after intracytoplasmic sperm injection: a novel, paired randomized controlled trial using DNA fingerprinting[J]. Fertil Steril, 2012, 98(3): 644-649.
[26] Cobo A, Diaz C. Clinical application of oocyte vitrification: a systematic review and meta-analysis of randomized controlled trials[J]. Fertil Steril, 2011, 96(2): 277-285.
[27] Glujovsky D, Riestra B, Sueldo C, et al. Vitrification versus slow freezing for women undergoing oocyte cryopreservation[J]. Cochrane Database Syst Rev, 2014(9): CD010047. doi:10.1002/14651858.
[28] Cascante SD, Blakemore JK, DeVore S, et al. Fifteen years of autologous oocyte thaw outcomes from a large university-based fertility center[J]. Fertil Steril, 2022, 118(1): 158-166.
[29] Chronopoulou E, Raperport C, Sfakianakis A, et al. Elective oocyte cryopreservation for age-related fertility decline[J]. J Assist Reprod Genet, 2021, 38(5): 1177-1186.
[30] Walker Z, Lanes A, Ginsburg E, et al. Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation[J]. Reprod Biol Endocrinol, 2022, 20(1): 10.
[31] Cobo A, García-Velasco JA, Remohí J, et al. Oocyte vitrification for fertility preservation for both medical and nonmedical reasons[J]. Fertil Steril, 2021, 115(5): 1091-1101.
[32] Cobo A, Rubio C, Gerli S, et al. Use of fluorescence in situ hybridization to assess the chromosomal status of embryos obtained from cryopreserved oocytes[J]. Fertil Steril, 2001, 75(2): 354-360.
[33] Noyes N, Porcu E, Borini A. Over 900 oocyte cryopreservation babies born with no apparent increase in congenital anomalies[J]. Reprod Biomed Online, 2009, 18(6): 769-776.
[34] Chian RC, Huang JY, Tan SL, et al. Obstetric and perinatal outcome in 200 infants conceived from vitrified oocytes[J]. Reprod Biomed Online, 2008, 16(5): 608-610.
[35] Cobo A, Serra V, Garrido N, et al. Obstetric and perinatal outcome of babies born from vitrified oocytes[J]. Fertil Steril, 2014, 102(4): 1006-1015.
[36] Van Reckem M, Blockeel C, Bonduelle M, et al. Health of 2-year-old children born after vitrified oocyte donation in comparison with peers born after fresh oocyte donation[J]. Hum Reprod Open, 2021, 2021(1): hoab002. doi: 10.1093/hropen/hoab002.
[37] Glujovsky D, Riestra B, Sueldo C, et al. Vitrification versus slow freezing for women undergoing oocyte cryopreservation[J]. Cochrane Database Syst Rev, 2014(9): CD010047. doi:10.1002/14651858.
[38] Da Luz CM, Caetano MA, Berteli TS, et al. The impact of oocyte vitrification on offspring: a systematic review[J]. Reprod Sci, 2022. doi: 10.1007/s43032-022-00868-4.
[1] LI Hongwen, ZHOU Zifu, WANG Song, HUO Ran. Cost-effectiveness analysis of staged excision compared with one-stage excision of facial pigmented nevus in children [J]. Journal of Shandong University (Health Sciences), 2022, 60(7): 123-128.
[2] DONG Xue, ZHAO Xia, CHENG Zijie, HAN Yi. Pharmacoeconomic evaluation of levosimendan and milrinone in the treatment of 711 patients with severe heart failure complicated with renal injury [J]. Journal of Shandong University (Health Sciences), 2022, 60(4): 91-98.
[3] WANG Chuanxin. Liquid biopsy of tumor [J]. Journal of Shandong University (Health Sciences), 2021, 59(9): 64-71.
[4] CHEN Wei, GUO Qingqing, XU Jin, FANG Yuan, SUN Mei, SHENG Yan. A comparative analysis of the effects of natural cycle combined with luteal ovarian stimulation and dual ovarian stimulation [J]. Journal of Shandong University (Health Sciences), 2021, 59(8): 61-66.
[5] Hongling WEN,Xiaoying XU. Prevention and control of emerging viral infectious diseases and biosafety [J]. Journal of Shandong University (Health Sciences), 2021, 59(5): 40-45.
[6] HUANG Ping, SHANG Hongguo. Clinical application of digital implant guide in the absence of continuous multiple teeth in the mandibular posterior tooth area [J]. Journal of Shandong University (Health Sciences), 2020, 58(2): 60-63.
[7] XU Ling, SUN Yan, CHEN Liang, WANG Xiwen. Application of mixed reality technique in the resection of benign lateral skull base tumor [J]. Journal of Shandong University (Health Sciences), 2020, 58(1): 31-38.
[8] ZENG Yanbing, WANG Qiupeng, FANG Ya. Health economic evaluation of “co-management of doctors of three kinds”of diabetes patients in Xiamen [J]. Journal of Shandong University (Health Sciences), 2019, 57(8): 89-94.
[9] RUAN Xiangyan, CHENG Jiaojiao, DU Juan, LI Yanglu, JIN Fengyu, Alfred O. MUECK. Research progress of fertility preservation methods [J]. Journal of Shandong University (Health Sciences), 2019, 57(2): 29-34.
[10] ZHANG Yingchun. Safety of human assisted reproductive technology offspring [J]. Journal of Shandong University (Health Sciences), 2019, 57(10): 52-59.
[11] HAO Guimin, LUO Zhuoye, CUI Na. Hazards of common complications in assisted reproductive technology [J]. Journal of Shandong University (Health Sciences), 2019, 57(10): 7-12.
[12] CHONG Tie, CHEN Qi. Clinical application of mirabegron in the treatment of overactive bladder [J]. Journal of Shandong University (Health Sciences), 2018, 56(3): 6-11.
[13] WANG Xiaoya, LI Jiayu, GUO Jing, ZHANG Lihong. A comparative study of the effectiveness between surgically assisted rapid palatal expansion and miniscrew-assisted rapid palatal expansion in adults [J]. Journal of Shandong University (Health Sciences), 2018, 56(12): 55-61.
[14] LÜ Huimin, ZHANG Mengwei, NIU Limin, ZENG Huiai, YAN Min. Efficacy and safety of single-agent domestic docetaxel in the treatment of advanced breast cancer [J]. Journal of Shandong University (Health Sciences), 2018, 56(1): 45-49.
[15] JIAO Fengping, ZHANG Haitao, ZHAO Yinghui, TIAN Zhaoju, YANG Shulin. Preliminary study of tissue distribution and safety of HSV-2 DNA vaccine in mice [J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(7): 38-42.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] MA Qingyuan, PU Peidong, HAN Fei, WANG Chao, ZHU Zhoujun, WANG Weishan, SHI Chenhui. Effect of miR-27b-3p regulating SMAD1 on osteosarcoma cell proliferation, migration and invasion[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 32 -37 .
[2] SUO Dongyang, SHEN Fei, GUO Hao, LIU Lichang, YANG Huimin, YANG Xiangdong. Expression and mechanism of Tim-3 in animal model of drug-induced acute kidney injury[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 1 -6 .
[3] LONG Tingting, XIE Ming, ZHOU Lu, ZHU Junde. Effect of Noggin protein on learning and memory abilities and the dentate gyrus structure after cerebral ischemia reperfusion injury in mice[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 15 -23 .
[4] LI Ning, LI Juan, XIE Yan, LI Peilong, WANG Yunshan, DU Lutao, WANG Chuanxin. Expression of LncRNA AL109955.1 in 80 cases of colorectal cancer and its effect on cell proliferation, migration and invasion[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 38 -46 .
[5] ZHANG Baowen, LEI Xiangli, LI Jinna, LUO Xiangjun, ZOU Rong. miR-21-5p targeted TIMP3 to inhibit proliferation and extracellular matrix accumulation of mesangial cells in Type II diabetic nephropathy mice[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 7 -14 .
[6] FU Jieqi, ZHANG Man, ZHANG Xiaolu, LI Hui, CHEN Hong. Molecular mechanism of Toll-like receptor 4 in the aggravation of blood lipid accumulation by inhibiting the peroxisome proliferator-activate receptor γ[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 24 -31 .
[7] DING Xiangyun, YU Qingmei, ZHANG Wenfang, ZHUANG Yuan, HAO Jing. Correlation of the expression of insulin-like growth factor II in granulosa cells and ovulation induction outcomes of 84 patients with polycystic ovary syndrome[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 60 -66 .
[8] XU Yuxiang, LIU Yudong, ZHANG Peng, DUAN Ruisheng. A retrospective analysis of risk factors of cerebral microbleeds in 101 patients with cerebral small vessel disease[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 67 -71 .
[9] SHI Shuang, LI Juan, MI Qi, WANG Yunshan, DU Lutao, WANG Chuanxin. Construction and application of a miRNAs prognostic risk assessment model of gastric cancer[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 47 -52 .
[10] GUO Zhihua, ZHAO Daqing, XING Yuan, WANG Wei, LIANG Leping, YANG Jing, ZHAO Qianqian. Single-stage end-to-end anastomosis in the management of severe cervical tracheal stenosis[J]. Journal of Shandong University (Health Sciences), 2020, 1(7): 72 -76 .