JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2017, Vol. 55 ›› Issue (3): 59-63.doi: 10.6040/j.issn.1671-7554.0.2016.481

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Correlation between porphyromonas gingivalis FimA genotype V and ginival inflammatory in the orthodontic patients

SUN Fei1, LI Shuxiang2, WANG Lin1,3, ZHANG Li3, XIAO Shuiqing1,3   

  1. 1. College of Dentistry, Binzhou Medical University, Binzhou 256603, Shandong, China;
    2. Department of Stomatology, Zhangqiu Peoples Hospital, Jinan 250200, Shandong, China;
    3. Department of Orthodontics, Jinan Stomatological Hospital, Jinan 250001, Shandong, China
  • Received:2016-02-02 Online:2017-03-10 Published:2017-03-10

Abstract: Objective To explore the correlation between the gene expression of FimA genotype V of Porphyromonas gingivais(P.g)and gingival inflammatory in orthodontic patients. Methods Totally 61 patients with healthy gingiva were randomly selected. Their gingival crevicular fluid(GCF)was collected before and 3 months after orthodontic treatment. The content of P.g and FimA genotype V in the GCF was detected with PCR technique. Results The detection rate of P.g and FimA genotype V were 26.23% vs 73.77%, and 9.84% vs 26.23% before and after orthodontic treatment, showing significant difference(P<0.01, P<0.05). Conclusion Three months after patients wore appliance, the detection rate of P.g and FimA genotype V were positively correlated to gingival inflammation index. The detection rate of FimA genotype V rose with increased gingival index. FimA genotype V can cause gingival inflammatory in orthodontic patients.

Key words: Porphyromonas gingivais, FimA genotype V, Orthodontic treatment, Gingivitis

CLC Number: 

  • R783.5
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