Abstract: Objective To evaluate the value of airway stent placement by electronic bronchoscopy on malignant airway stenosis with one side lung ventilation. Methods Thirty-four patients in the Department of Respiratory Disease of Central Hospital of Wuhan from January 2011 to February 2015 were included. Airway stent was used to evaluate the short-term therapeutic effects, airways opening degree, pulmonary functions and complications. Results Follow up for one month, the symptoms of dyspnea were relieved. Airway diameter, dyspnea score, forced expiratory volume in one second(FEV1), partial pressure of oxygen(PaO₂), partial pressure of carbon dioxide(PaCO₂)were improved significantly(P<0.05). Adverse reactions in 2 weeks were cough(7 cases, 20.59%), sore throat(9 cases, 26.47%), and hemoptysis(10 cases, 29.41%). With the follow-up for one month,airway granulation proliferation occurred in 3 patients(8.82%), sputum drainage difficulty in 5 patients(14.71%), and 1 patient(2.94%)died because of massive hemoptysis after 27 days. Conclusion Stent placement by electronic bronchoscopy for malignant airway stenosis with one side lung ventilation is effect and safe, worthy to be promoted clinically.

Key words: Airway stent, Malignant airway stenosis, One side lung ventilation