JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (6): 54-57.doi: 10.6040/j.issn.1671-7554.0.2014.718

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Application of Onodera prognostic nutrition index in elderly patients with esophageal carcinoma treated with radiotherapy

YANG Shengsi, CHENG Yufeng   

  1. Department of Radiotherapy, Qilu Hospital of Shandong University, Jinan 250012, Shandong, China
  • Received:2014-10-17 Revised:2015-03-19 Published:2015-06-10

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Abstract: Objective To explore the applicative value of Onodera prognostic nutrition index (Onodera index) in elderly patients with esophageal carcinoma treated with radiotherapy. Methods Onodera index of 93 elderly patients with esophageal squamous-cell carcinoma treated with only radiotherapy were collected, and the patients were divided into good-nourishment group (Onodera index ≥45) and poor-nourishment group (Onodera index <45). Correlations between Onodera index and clinicopathological features, quality of life, radiation esophagitis and tumor regression were analyzed. Results Onodera index was found to be related to tumor size (P=0.002) and distant metastases (P=0.024). Good-nourishment group had significantly better quality of life especially therapeutic attitude (P=0.036), food intake (P=0.043) and self-care ability (P=0.028) than poor-nourishment group. Patients in poor-nourishment group had significantly more serious radiation esophagitis than those in good-nourishment group (P=0.032), while there was no significant difference in tumor regression between the two groups (P>0.05). Conclusion Onodera index is a valuable clinical indicator to estimate the nutritional status, clinicopathological features and early complications of elderly esophageal carcinoma patients treated with radiotherapy.

Key words: Elderly patients, Onodera prognostic nutrition index, Esophageal carcinoma, Radiotherapy

CLC Number: 

  • R735.1
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