Journal of Shandong University (Health Sciences) ›› 2021, Vol. 59 ›› Issue (9): 37-42.doi: 10.6040/j.issn.1671-7554.0.2021.0966

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Progress on the activation of endogenous stem cells and functional repair in LIPUS mechanotransduction

XIA Shujie, GUAN Yanjie   

  1. Department of Urology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200080, China
  • Published:2021-10-15

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Abstract: In recent years, mechanical therapies represented by low-intensity pulsed ultrasound(LIPUS)have been widely used in rehabilitation medicine, fracture repair, nerve injury repair, urinary system diseases and other fields. Current studies have shown that LIPUS may participate in tissue repair by activating endogenous stem cells, but the specific mechanism by which mechanical force activates stem cells through the transformation of the biological chain is still unclear. Therefore, further exploration of the conduction process of mechanotransduction will help to reveal the mechanism of LIPUS and provide reference for subsequent researches and clinical applications.

Key words: Low-intensity pulsed ultrasound, Mechanotransduction, Endogenous stem cells

CLC Number: 

  • R691
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