经导管介入治疗主动脉瓣下边缘<2 mm的室间隔缺损疗效评价

doi:10.6040/j.issn.1671-7554.0.2016.1145

Abstract

Abstract: Objective To explore the feasibility and safety of transcatheter closure of ventricular septal defect(VSD)with subaortic rim less than 2 mm. Methods The clinical data of 156 patients with VSD who underwent percutaneous interventional procedure during May 2010 and May 2016 were retrospectively reviewed. According to the subaortic rim by transthoracic echocardiography, the patients were divided into short rim group(<2 mm, n=69)and long rim group(≥2 mm, n=87). The success rate and complications were compared. The risk factors of failure in short rim group were studied with Logistic regression analysis. Results The success rate of short rim group and long rim group was 78.3% vs 96.6%(P<0.01). Complications in the short rim group included trivial aortic regurgitation in 5 cases, heart arrhythmia in 23 cases and trivial residual shunt without mechanical hemolysis in 6 cases. Complications in the long rim group included trivial aortic regurgitation in 1 case, heart arrhythmias in 14 cases, residual shunt in 6 cases and mechanical hemolysis in 2 cases. Logistic regression analysis revealed aortic valve prolapse before procedure(OR=8.8, 95%CI: 1.4-54.9, P=0.02)and defects ≥5 mm(OR=11.6, 95%CI: 2.37-57.11, P=0.003)were independent 山东大学学报 (医学版)55卷8期 -赵立健,等.经导管介入治疗主动脉瓣下边缘<2 mm的室间隔缺损疗效评价 \=-risk factors of failure. Conclusion Transcatheter closure of VSD with subaortic rim <2 mm has relatively lower success rate. Short subaortic rim combined with aortic valve prolapse before procedure and defects ≥5 mm were independent risk factors of failure. Therefore, indications of interventional procedure for VSD with short subaortic rim should be strictly selected.

Key words: Ventricular septal defect, Subaortic rim, Residual shunt, Atrioventricular block, Aortic regurgitation

CLC Number:

R725.4

ZHAO Lijian, HAN Bo, ZHANG Jianjun, YI Yingchun, JIANG Diandong, LÜ Jianli, WANG Jing. Feasibility and safety of transcatheter closure of ventricular septal defect with subaortic rim <2 mm[J].JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2017, 55(8): 52-56.

References

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Feasibility and safety of transcatheter closure of ventricular septal defect with subaortic rim <2 mm

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