Abstract:

Objective   To investigate protective effects of vitamin E and zinc supplement on the influence by a certain time phone calls in pregnant rats and offspring． Methods   Sixty pregnant rats were randomly divided into six groups. All groups were exposed to a certain intensity of cell phone radiation for 1 hour each time，3 times per day for 21 days from the first day of pregnancy． The negative control group and positive control group were given vitamin E removed peanut oil , whereas the low, middle and high dose groups were administered 5,15 and 30mg/mL vitamin E peanut oil, respectively. Combined intervention group was supplemented with 15mg/mL vitamin E peanut oil and 10mg/mL sulfuric acid zinc. C3, C4, IgG, IgA and IgM levels in maternal and offspring’s serum were determined after the delivery． Results   In the positive control group, the levels of C3 and IgG in the dams and offspring rats and of C4 in the parent rats significantly reduced when compared to the negative controls (P<0.05). Compared with the positive group the C3, C4 and IgG levels in maternal and the C3, IgG levels in offspring rats increased significantly in vitamin E high dose and vitamin E+Zn combined group (P<0.05). The level of C3 in vitamin E middle dose group of mothers was also increased significantly (P<0.05). The IgG levels of offspring rats in middle, high dosages groups all increased and the differences were significant when compare to the control croup (P<0.05). The differences of C3 levels in the offspring rats and the C4 levels in maternal rats between combination group and middle dose group were significant (P<0.05). Conclusion   Vitamin E has a protective effect against damage to C3, C4, IgG induced by a certain time phone calls in pregnant mice and neonatal rat. Vitamin E combined with zinc has synergistic effect.

Key words: Vitamin E; Zn; Cell phones; Complements; Immunoglobulin