Abstract:

Objective   To assess the relationship of all dissected and negative lymph nodes number to the prognosis of patients after pancreatic cancer radical surgery. Methods   Two hundred and twenty-seven  patients with pancreatic carcinoma who underwent radical resection from 1998 to 2007 in Qilu Hospital of Shandong University were involved. The relationship of the all dissected and negative LNs number to the survival of patients was analyzed. Results   A total of 182 patients were obtained with the follow-up rate of 80.2%. There were 76 patients with no lymph node metastasis. The 3-year survival rate and 5-year survival rate was 28.9% and 21.0% respectively. The number of all dissected LNs was the independent predictor. The 3-year survival rate and 5-year survival rate of the rest 106 patients with lymph node metastasis was 21.1% and 7.5%. The numbers of all dissected LNs and negative LNs were independent predictors. The all dissected LNs number was positively correlated with negative LNs number on the Pearson's correlation test(r=0.919, P＜0.05). Conclusion   With the standard radical surgery, the all dissected LNs and negative LNs numbers can be TNM stage auxiliary indicators for the prognosis of pancreatic cancer patients, so that patients can get more accurate clinical stages and prognostic judgment and the best longterm survival rate.

Key words: Pancreatic neoplasm； Lymph node； Influencing factor； Relevance； Prognosis