JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2012, Vol. 50 ›› Issue (1): 109-112.

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Clinical features and treatment of intraparenchymal epidermoid cyst in the brain

ZHAO Duan-yun1， CHI Ling-yi1， ZHOU Xu-dong1， WANG Jie2， HU Ke3， SHAO Yi1   

  1. 1. Department of Neurosurgery， Qilu Hospital of Shandong University， Jinan 250012， China；
    2. Department of Physical Medicine & Rehabilitation， Qilu Hospital of Shandong University， Jinan 250012， China；
    3. Department of  Cardiology， Provincial Hospital Affiliated to Shandong University， Jinan  250021， China
  • Received:2011-04-25 Online:2012-01-10 Published:2012-01-10

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Abstract:

Objective   To explore clinical features and treatment of intraparenchymal epidermoid cyst in the brain. Methods   Clinical manifestations，imaging findings and surgical treatment were retrospectively analyzed in 27 intraparenchymal epidermoid cysts in the brain.  Factors affecting the occurrence of aseptic meningitis were analyzed by statistical methods. Results   20 cases of tumors were completely removed， and 7 cases were sub- totally removed. After surgery， 1 patient died， 7 were improved, and 3 had tumor recurrence. Statistical analysis showed that aseptic meningitis was related to the diameter of the tumor， use of prophylactic lumbar puncture， complete resection and irrigation on tumor  bed by dexamethasone solution with normal saline, and the former two factors were most important by Logistic regression analysis. Conclusion   Complete resection of tumors，use of prophylactic lumbar puncture and irrigation on tumor bed by dexamethasone solution with normal saline could reduce the occurrence of aseptic meningitis.

Key words: Central nervous system neoplasms； Epidermoid cyst； Intraparenchyma； Aseptic meningitis

CLC Number: 

  • R651.1
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