Abstract:

Objective    To analyze expressions of regulatory T cells and  helper T lymphocytes in the peripheral blood of pregnancy induced hypertension (PIH) women. Methods     27 PIH women were selected to detect regulatory T cells (CD+4CD+25 Treg and CD+4CD+25 Foxp3+Treg) and helper T lymphocytes (CD+3、CD+4、CD+8、CD+4/CD+8) in the peripheral blood, and the testing results were compared with another 20 normal pregnant women during the same hospitalization. Results     Levels of CD+4CD+25 Treg and CD+4CD+25 Foxp3+ Treg of the regulatory T cells in the PIH women were significantly lower than those in the control group(P<0.05-0.01).  Level of CD+4/CD+8 of helper T lymphocytes in the PIH women was significantly higher than that in the control group(P<0.050.01), but level of CD+8 in the PIH women was significantly lower than that in the control group (P<0.05-0.01). Conclusion     It is clearly indicated that expressions of  regulatory T cells and  helper T lymphocytes in the peripheral blood of PIH women are out of the normal range.

Key words: Pregnancy induced hypertension; Regulatory T cells； Helper T lymphocyte; Peripheral blood