Abstract:

Objective    The objective of this paper is to investigate the effects of Shenqi Fuzheng Injection Powder on immune function and immune regulation of mice after intravenous injection. Methods    Each test needs 50 KM mice (25 male and 25 female).These 50 KM mice were randomly divided into five groups (Group Veh, Group 20mg/10g, Group 40mg/10g， Mand 80mg/10g of Shenqi Fuzheng Injection Powder as well as Group 0.8mL/10g of Shenqi Fuzheng Injection)according to their body weight. After being treated intravenously for 7 days, detected the immune parameters like the index of organs， the number of hemolysis plaque, the level of serum hemolysin, the delayed hypersensitivity， the transform and proliferation of T lymphocytes， the index of carbon clearance as well as the cyto activity of NK cells. Results    Compared with Group Veh, there were significant statistical differences（P< 0.05 or P<0.01）of the index of organs， the number of hemolysis plaque, the level of serum hemolysin,the delayed hypersensitivity， the transform and proliferation of T lymphocytes， the index of carbon clearance as well as the cyto activity of NK cells were found in the group of Shenqi Fuzheng Injection Powder of 40, 80mg/10g and Shenqi Fuzheng injection of 0.8mL/10g after the intravenous administration; while compared with Group Veh, the index of carbon clearance and the cyto activityof NK cells also showed significant statistical differences（P<0.05）in the group of Shenqi Fuzheng Injection Powder of 20mg/10g after the intravenous administration. Conclusion     From the experimental results, it can be speculated that Shenqi Fuzheng Injection Powder can enhance the non-specific and specific immune function on mice, and the immune function of the organism can be effectively improved.

Key words: Shenqi Fuzheng Injection Powder； Mice； Immune function； Organ index