JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2010, Vol. 48 ›› Issue (5): 131-134.

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The comparison study of the blood supply of hepatic VX2 tumor by contrast-enhanced ultrasonography through the peripheral vein and portal vein

XIAO Jing, LI Jie, WEI Yun, SHI Dandan   

  1. Department of Ultrasound, Qilu Hospital of Shandong University, Jinan 250012, China
  • Received:2010-01-14 Online:2010-05-16 Published:2010-05-16

Abstract:

Objective  To evaluate the blood supply of hepatic tumor by contrast-enhanced ultrasonographythrough peripheral and portal veins. Methods  An in vivo model was studied using SonoVueTM and low mechanical index (MI) real-time gray-scale contrast-enhanced ultrasonography. SonoVueTM was rapidly injected into 12 New Zealand white rabbits with hepatic VX2 tumor through the marginal ear vein and the main trunk of the portal vein respectively. The characteristic of blood supply and enhancement pattern were analyzed. Results  SonoVueTM was administrated into 12 rabbits with 12 tumors through the peripheral vein: the tumors showed hyperechoic enhancement in the arterial phase and hypoechoic enhancement in the postarterial phase. Ultrasonographic portography was perfomed in 12 rabbits with 22 tumors: seven tumors enhanced diffusely; three tumors showed the branches of the portal vein; five tumors showed peripheral irregular enhancement; seven tumors showed no obvious enhancement. Conclusion  Contrast-enhanced ultrasonography through the peripheral vein and portal vein can manifest the blood supply of hepatic tumor, so it may be useful in the qualitative diagnosis and individual treatment of hepatic tumor.

Key words: Ultrasonography; Contrast media; Liver neoplasms; Portography

CLC Number: 

  • R735.7
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