Abstract: To investigate the causes for vesania in postrenal transplantation patients. Methods： We reviewed and analyzed the process of diagnosis and treatment of 9 patients caught vesania after kidney transplantation. They were all treated using sedatives, 8 of them were transfused using Diazepam, the largest dosage was 90mg within 24 hours.However, 5 of them still showed the symptom of vesania after transfusion, so they were injected with 25?mg Chlorpromazine and 25?mg Promethazine. Results： After being used sedative, the patients were calmed down gradually and then could be treated easily, 5 of the patients were in the state of lethargy with stable vital signs. After 24 to 72 hours, patients were given less sedative till not according to their condition. Being stable, 8 patients were discharged 2872 days later. The transplanted kidney of one sufferer was broken due to anxious. After nephrectomy, he was given Diazepam, and the symptom disappeared 28 hours later. One year later, He accepted transplantation and no symptom of vesania reappeared. Conclusions： Vesania after kidney transplantation contributes to comprehensive causes.

Key words: Kidney transplantation, Mental disorder, Operation