自身免疫性郎飞结病磁共振成像研究进展

doi:10.6040/j.issn.1671-7554.0.2024.1330

Abstract

Abstract: Autoimmune nodopathies(AN)is a type of autoimmune disease involving autoantibodies, particularly the lgG4 subtype, that act on demyelinating pathological changes on the node of Ranvier. These changes produce a series of clinical manifestations of peripheral neuropathy, collectively referred to as nodo-paranodopathy. Currently, research on AN primarily focuses on their clinical, pathological, and immunological characteristics. Diagnosis mainly depends on invasive examinations, such as antibody detection and cerebrospinal fluid analysis. Magnetic resonance imaging(MRI)of the peripheral nerves has been increasingly used as a noninvasive method to evaluate peripheral nerve diseases. Focusing on the morphological and quantitative changes of different peripheral nerve diseases continuously can help us better understand the potential pathophysiological processes of these diseases, providing theoretical support for their diagnosis and treatment evaluation. Thus, this article reviews the application of lumbosacral plexus magnetic resonance imaging in AN to provide supporting evidence for early clinical diagnosis, differential diagnosis, and the development of accurate treatment plans.

Key words: Magnetic resonance neurography, Autoimmune nodopathies, Chronic inflammatory demyelinating polyradiculoneuropathy, Guillain-Barre Syndrome, Antibodies

CLC Number:

R445.2

SHAN Tixiao, DU Weichen, WANG Qinzhou, LI Anning, LI Chunhai. Research progress of magnetic resonance imaging in autoimmune nodopathies[J].Journal of Shandong University (Health Sciences), 2025, 63(11): 117-122.

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