Journal of Shandong University (Health Sciences) ›› 2019, Vol. 57 ›› Issue (9): 97-103.doi: 10.6040/j.issn.1671-7554.0.2019.594

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MR-diffusion tensor image and diffusion kurtosis image of spatio-temporal development of new-born cerebral cortex

WANG Lifeng1, LI Zheng2, YÜ Qiaowen2   

  1. 1. Department of Obstetrics, Shandong Maternal and Child Health Hospital, Jinan 250014, Shandong, China;
    2. Department of Radiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China
  • Published:2022-09-27

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Abstract: Objective To explore the spatio-temporal development of newborn cerebral cortex by describing the changes of parameters from diffusion tensor image(DTI)and diffusion kurtosis image(DKI)with newborns with different gestational ages. Methods The T1WI and multiple-shell DWI data of brain of newborn with gestational age ranging from 36.6 to 44.4 weeks were obtained. The diffusion parameters including fractional anisotraphy(FA), mean diffusivity(MD), axial diffusivity(AD), radial diffusivity(RD)and mean kurtosis(MK)were analyzed with GBSS method. Results Dramatic decrease of FA and AD values were detected from cerebral cortex before 40 gestational weeks(frontal lobe AD: β=-0.49, P=0.01; parietal lobe FA: β=-0.48, P=0.02; parietal lobe AD: β=-0.62, P=0.003; temporal lobe FA: β=-0.44, P=0.04; temporal lobe AD: β=-0.5, P=0.01; occipital lobe FA: β=-0.53, P=0.01; occipital lobe AD: β=-0.55, P=0.009), while no significant result was found within any lobe after 40 PCW. The frontal lobe had higher developmental rate than the occipital lobe(F=9.36, P=0.004). The changes of MK values supplemented the information of cerebral cortex microstructure changes. Conclusion The differences among changes of parameters from DTI and DKI data in the time and spatial dimensions reflect the spatio-temporal development of cerebral cortex 山 东 大 学 学 报 (医 学 版)57卷9期 -王丽凤,等.足月新生儿大脑皮质时间-空间异质性发育的磁共振弥散张量及弥散峰度 \=-of newborn.

Key words: Newborn, Cerebral cortex, Spatial-temporal development, Diffusion image of multi-spherical shell

CLC Number: 

  • R742.8
[1] Girardi G. MRI-based methods to detect placental and fetal brain abnormalities in utero[J]. J Repord Ommunol, 2016, 114: 86-91. doi: 10.1016/j.jri.2015.05.008.
[2] Yu Q, Ouyang A, Chalak L, et al. Structural development of human fetal and preterm brain cortical plate based on population-averaged templates[J]. Cerebral Cortex, 2016, 26(11): 4381-4391.
[3] Neto Henriques R, Correia MM, Nunes RG, et al. Exploring the 3D geometry of the diffusion kurtosis tensor—impact on the development of robust tractography procedures and novel biomarkers[J]. Neuroimage, 2015, 111: 85-99. doi: 10.1016/j.neuroimage.
[4] Guerreri M, Palombo M, Caporale A, et al. Age-related microstructural and physiological changes in normal measured by MRI by MRI MRI by MRI MRI by MRI procedures and novel biomarkers[J]. Neuroimage, 2019, 188: 654-667. doi: 10.1016/j.neuroimage.
[5] Sours C, Raghavan P, Medina AE, et al. Structural and functional integrity of the intraparietal sulcus in moderate and severe traumatic brain injury[J]. J Neurotrauma, 2017, 13(7): 1473-1481.
[6] Adisetiyo V, Tabesh A, Di Martino A, et al. Attention-deficit/hyperactivity disorder without comorbidity is associated with distinct atypical patterns of cerebral microstructural development[J]. Hum Brain Mapp, 2014, 35(5): 2148-2162.
[7] Kochunov P, Rowland LM, Fieremans E, et al. Diffusion-weighted imaging uncovers likely sources of processing-speed deficits in schizophrenia[J]. PNAS, 2016, 113(47): 13504-13509.
[8] Zhang J, Chen X, Chen D, et al. Grading and proliferation assessment of diffuse astrocytic tumors with monoexponential, biexponential, and strectched-exponential diffusion-weighted imaging and diffusion kurtosis imaging[J]. Eur J Radiol, 2018, 109: 188-195. doi: 10. 1016/ j.ejrad. 2018. 11.003.
[9] Vanhoutte G, Pereson S, Delgado Y Palacios R, et al. Diffusion kurtosis imaging to detect amyloidosis in an APP/PS1 mouse model for Alzhermers disease[J]. Magn Reson Med, 2013, 69(4): 1115-1121.
[10] Shi J, Chang L, Wang J. et al. Initial application of diffusion kurtosis imaging in evaluating brain development of healthy preterm infants[J]. PLoS One, 2016, 11(4): e0154146.
[11] Bouyssi-Lobar M, Brossard-Rocine M, Jacobs M, et al. Regional microstructural organization of the cerebral cortex is addercted by preterm birth[J]. Neuroimage Clin, 2018, 18: 871-880. doi:10.1016/j.nicl.2018.03.020.
[12] Pavlidis E, Lioyd RO, Boylan GB. EEG-a valuable biomarker of brain injury in perterm infants[J]. Dev Neurosci, 2017, 39(1-4): 23-35.
[13] Leung MP, Thompson B, Black J, et al. The effects of preterm birth on visual development[J]. Clin Exp Optom, 2018, 101(1): 4-12.
[14] Kim ST, Kim H, Kim HH, et al. A rare case of lethal prenatal-onset infantile cortical hyperostosis[J]. Yonsei Med J, 2019, 60(5): 484-486.
[15] Tataranno ML, Perrone S, Longini M, et al. Predictive role of urinary metabolic profile for abnormal MRI score in preterm neonates[J]. Dis Markers, 2018, 2018:4938194. doi:10.1155/2018/4938194.
[16] Jin C, Li Y, Wang M, et al. Proper timing for the evaluation of neonatal brain white matter development: a diffusion tensor imaging study[J]. European Radiology, 2018, 29(3): 1527-1537.
[17] Baldoli C, Scola E, Della Rosa PA, et al. Maturation of preterm newborn brains: a fMRI-DTI study of auditory processing of linguistic stimuli and white matter development[J]. Brain StructFunct, 2015, 220(6): 3733-3751.
[18] Ouyang M, Jeon T, Sotiras A, et al. Differential cortical microstructural maturation in the preterm human brain with diffusion kurtosis and tensor imaging[J]. Proc Natl Acad Sci USA, 2019, 19:.doi:10.1073/pnas.1812156116.
[19] 张冉, 肖新兰. 局灶性皮质发育不良的MR解剖与功能成像研究进展[J]. 临床放射学杂志, 2018, 336(7): 165-168.
[20] Urbain C, Sato J, Hammill C, et al. Converging function, structure, and behavioural features of emotion regulation in very preterm children[J]. Hum Brain Mapp, 2019, 40(11):3385-3397.
[21] Ball G, Srinivasan L, Aljabar P, et al. Development of cortical microstructure in the preterm human brain[J]. PNAS, 2013, 110(23): 9541-9546.
[22] Grinberg F, Maximov II, Farrher E, et al. Diffusion kurtosis metrics as biomarkers of microstructural development: A comparative study of a group of children and a group of adults[J]. Neuroimage, 2017, 144(Pt A): 12-22.
[23] Mckinstry RC, Mathur A, Miller JH, et al. Radial organization of developing preterm human cerebral cortex revealed by non-invasive water diffusion anisotropy MRI[J]. Cerebral Cortex, 2002, 12(12): 1237-1243.
[24] Melbourne A, Eaton-Rosen Z, Orasanu E, et al. Longitudinal development in the preterm thalamus and posterior white matter: MRI correlations between diffusion weighted imaging and T2 relaxometry[J]. Hum Brain Mapp, 2016, 37(7): 2479-2492.
[25] Dubois J, Dehaene-Lambertz G, Kulikova S, et al. The early development of brain white matter: a review of imaging studies in fetuses, newborns and infants[J]. Neuroscience, 2014, 276: 48-71. doi: 10.1016 /j.neurosci ence. 2013.12.044.
[26] Sur M, Cowey A. Cerebral cortex: function and development[J]. Neuron, 1995, 15(3): 497-505.
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