Journal of Shandong University (Health Sciences) ›› 2018, Vol. 56 ›› Issue (2): 18-22.doi: 10.6040/j.issn.1671-7554.0.2017.630

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Humidified heated high flow nasal cannula versus nasal continuous positive airway pressure for initial respiratory support of very low birth weight infants

JIANG Chunjie, QI Lu, XIAO Junchao, XUE Jiang   

  1. Department of Pediatrics, the Second Hospital of Shandong University, Jinan 250033, Shandong, China
  • Published:2022-09-28

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Abstract: Objective To assess the efficacy and safety of humidified heated high flow nasal cannula(HHHFNC)compared with nasal continuous positive airway pressure(NCPAP)for the initial respiratory support of very low birth weight(VLBW)infants. Methods A total of 106 VLBW infants with gestational age(GA)between 28-32 weeks who met the predefined criteria for noninvasive ventilation were randomized to either the HHHFNC group or NCPAP group. The evaluation indexes included the respiratory outcomes and the incidence of complications. Results The clinical data of 98 infants were analyzed. The incidence of nasal trauma was significantly lower in the HHHFNC group than in the NCPAP group(2.0% vs 14.6%, P=0.029). There were no differences in the other respiratory and clinical outcomes between the two groups(P>0.05). Conclusion Compared to NCPAP, HHHFNC appears to be safer while has a similar efficacy as an initial respiratory support in VLBW infants with GA between 28-32 weeks.

Key words: High flow nasal cannula, Nasal continuous positive airway pressure, Noninvasive ventilation, Very low birth weight infants

CLC Number: 

  • R722
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