JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2016, Vol. 54 ›› Issue (3): 45-49.doi: 10.6040/j.issn.1671-7554.0.2015.887

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Chemical constituents from the aerial parts of Litsea glutinosa(Lour.)C.B. Rob.

XU Youwei1, ZHOU Honglei1, REN Dongmei2, LOU Hongxiang2, SHEN Tao2   

  1. 1.Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong, China;
    2. Department of Pharmacognosy, School of Pharmaceutical Sciences, Shandong University, Key Lab of Chemical Biology Ministry of Education, Jinan 250012, Shandong, China
  • Received:2015-09-18 Online:2016-03-10 Published:2016-03-10

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Abstract: Objective To study the chemical constituents from the aerial parts of Litsea glutinosa(Lour.)C.B. Rob. Methods The obtained compounds were isolated by different chromatographic methods, including silica gel, Sephadex LH-20 and high performance liquid chromatography, and then their structures were elucidated on the basis of spectroscopic analyses, particularly the nuclear magnetic resonance spectroscopy. Results Five compounds were isolated from the EtOAc partition of the 95% EtOH extract of the aerial parts of Litsea glutinosa, and their structures were identified as pubinernoid A(I), vomifoliol(II), atroside(III), 1,2-dihydro-6,8-dimethoxy-7-1-(3,5-dimethoxy-4-hydroxyphenyl)- N1,N2-bis-［2-(4-hydroxyphenyl)ethyl］-2,3-naphthalene dicarboxamide(IV), and daucosterol(V). Conclusion Compounds I-IV are isolated from Litsea glutinosa for the first time, and compounds I-III are obtained from the genus of Litsea for the first time.

Key words: Litsea glutinosa, Chemical constituents, Structure identification

CLC Number: 

  • R284.2
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