JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (10): 42-45.doi: 10.6040/j.issn.1671-7554.0.2015.728

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Establishment of clinical database of Alzheimer's disease based on Web in Shandong Province

GE Shujian1,2, LIN Weiwei3, CONG Lin4, ZHANG Tao1, HAN Xiaojuan4, ZHANG Qinghua4, DU Yifeng4   

  1. 1. School of Public Health, Shandong University, Jinan 250012, Shandong, China;
    2. Department of Science and Education, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China;
    3. Department of Statistics and Medical Record Management, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China;
    4. Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China
  • Received:2015-08-03 Online:2015-10-10 Published:2015-10-10

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Abstract: Objective To establish Alzheimer's disease (AD) clinical database in Shandong Province and investigate its applications in the managements of clinical data, imaging data and examination results of AD patients. Methods The database was constructed based on J2EE framework, Oracle 10 g database, Browser/Server(B/S) structure and Java language. Results The clinical data, cognitive assessment, imaging results, biochemical examination results and follow-up information of AD patients were collected according to the following characteristics: AD clinical data standards, ID number and hierarchical management permissions. Based on this, AD outpatient cases database, early AD diagnosis database, AD epidemiological network were established, and AD medical quality monitoring research could be pursued. Conclusion This research can normalize related standards of AD database, formulate scientific and standardized process of early AD diagnosis, eliminate regional AD information islands in different medical institutions, and realize information sharing among all the business.

Key words: Alzheimer's disease, Information sharing, Clinical database, Web technology, Big data

CLC Number: 

  • R741
[1] Lucas-Carrasco R, Skevington SM, Gómez-Benito J, et al. Using the WHOQOL-BREF in persons with dementia: a validation study[J]. Alzheimer Dis Assoc Disord, 2011, 25(4):345-351.
[2] 邓卓霞,陆锦龙,何承诚.鼻咽癌病案信息数据库的开发及应用[J].中国医药指南,2012,10(17):667-668. DENG Zhuoxia, LU Jinlong, HE Chengcheng. The development and application of medical record information database nasopharyngeal carcinoma[J]. Chinese Medicine Guide, 2012, 10(17):667-668.
[3] 黄婷婷,刘加林.基于Web肿瘤数据库应用的系统评价[J].生物医学工程学杂志,2013,30(5):946-951. HUANG Tingting, LIU Jialin. Tumor database application system based on web[J]. Journal of Biomedical Engineering, 2013, 30(5):946-951.
[4] 顾颖.专科病例数据库建设现状与对策[J].中华医学图书情报杂志,2011,20(11):20-22. GU Ying. Specialized subject cases database construction present situation and the countermeasures[J]. Chinese Journal of Medical Library and Information Science, 2011, 20(11):20-22.
[5] McKhann GM, Knopman DS, Chertkow H, et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging and the Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease[J]. Alzheimer's Dementia, 2011, 7(3):263-269.
[6] Chan KY, Wang W, Wu JJ, et al. Epidemiology of Alzheimer's disease and other forms of dementia in China, 1990-2010: a systematic review and analysis[J]. Lancet, 2013, 381:2016-2023.
[7] Sandmeier B, Jäger VK, Nagy G, et al. Autopsy versus clinical findings in patients with systemic sclerosis in a case series from patients of the EUSTAR database[J]. Clin Exp Rheumatol, 2015, 91(4):75-79.
[8] Mosnier A, Caini S, Daviaud I, et al. Clinical characteristics are similar across type A and B influenza virus infections[J]. PLoS One, 2015, 10(9):612-615.
[9] Lee H, Chapiro J, Schernthaner R, et al. How I do it: a practical database management system to assist clinical research teams with data collection, organization, and reporting[J]. Acad Radiol, 2015, 22(4):527-533.
[10] Athanasiadis EI, Antonopoulou K, Chatzinasiou F, et al. A Web-based database of genetic association studies in cutaneous melanoma enhanced with network-driven data exploration tools[J]. Database (Oxford), 2014, 11(2):1124-1128.
[11] 鄂琪敏,刘加林,黎勇. 基于Web的一体化喉癌临床数据库的构建及应用[J].临床耳鼻喉头颈外科杂志, 2014, 28(15):1181-1184.E Qimin, LIU Jialin, LI Yong. A web-based integrated clinical database construction and application of laryngeal cancer[J]. Journal of Clinical Otolaryngology Head and Neck Surgery, 2014, 28(15):1181-1184.
[12] Ferré M, Caignard A, Milea D, et al. Improved locus-specific database for OPA1 mutations allows inclusion of advanced clinical data[J]. Hum Mutat, 2015, 36(1):20-25.
[13] 王兵,陈颖超,梁永康,等.结直肠癌多学科专业数据库的初步建立[J].上海交通大学学报:医学版,2011,31(7):1055-1056.WANG Bing, CHEN Yingchao, LIANG Yongkang, et al. Colorectal cancer multidisciplinary professional database preliminary established[J]. Journal of Shanghai Jiaotong University: Medical Edition, 2011, 31(7):1055-1056.
[14] Bergamino M, Hamilton DJ, Castelletti L, et al. Brain tumor database, a free relational database for collection and analysis of brain tumor patient information[J]. Health Informatics J, 2015, 21(1):36-45.
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