JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES) ›› 2015, Vol. 53 ›› Issue (11): 32-36.doi: 10.6040/j.issn.1671-7554.0.2015.252

• Preclinical Medicine • Previous Articles     Next Articles

Antioxidant activities of aqueous extract from peony (Paeonia suffruticosa Andr.) flower

LI Zhaoping1, CHEN Liyong2, YIN Yingchao3, XU Guifa1   

  1. 1. Institute of Nutrition and Food Hygiene, School of Public Health, Shandong University, Jinan 250012, Shandong, China;
    2. Department of Nutrition, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, Shandong, China;
    3. Heze Peony Yao and Shun Biotechnology Co. Ltd., Heze 274000, Shandong, China
  • Received:2015-03-08 Online:2015-11-10 Published:2015-11-10

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Abstract: Objective To explore the anti-oxidative effect of aqueous extract from peony flower. Methods The total flavonoid content in aqueous extract was determined by the AlCl3 colorimetric method,and the total phenolic content was determined by the Folin-Ciocalteu method. The in vitro antioxidant abilities of peony flower aqueous extract were estimated by ABTS and DPPH radical scavenging activity. Its in vivo antioxidant ability was evaluated according to the superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activities, and malondialdehyde (MDA) content in serum and liver tissue of mice model with peroxidation induced by gastric gavage of 50% ethanol (12 mL/kg) for one time. Results The flavonoid content of aqueous extract from peony flower is (15.81±2.66) mg rutin/g and total phenolic acid content is (46.63±5.05) mg gallic acid/g. Extracts showed potent antioxidant activity according to ABTS, DPPH free radical scavenging method. Oral administration with high dose of aqueous extract of peony flower [500 mg/(kg·d)] for 30 days significantly improved activity of antioxidant enzymes (P<0.05) and reduced the content of MDA (P<0.05) in serum and liver tissue of the ethanol-induced peroxidation mice model. Conclusion The peony flower extracts with high total phenolic and flavonoid content possess remarkable antioxidant capacity.

Key words: Radical scavenging, Peony flower, Antioxidant capacity, Antioxidant enzymes, Malondialdehyde

CLC Number: 

  • R151.3
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