山东大学学报 (医学版) ›› 2025, Vol. 63 ›› Issue (2): 95-103.doi: 10.6040/j.issn.1671-7554.0.2024.0176
肖长春,余林玲,鄢德瑞,朱昱
XIAO Changchun, YU Linling, YAN Derui, ZHU Yu
摘要: 目的 探讨合肥市空气O3暴露对儿童呼吸系统疾病急诊就诊量影响。 方法 收集合肥市某儿童医院2017年1月1日至2019年12月31日逐日儿童急诊就诊资料、空气污染物监测资料和气象资料。基于分布滞后非线性模型(distributed lag non-linear model, DLNM)评估不同质量浓度O3对儿童呼吸系统疾病急诊就诊量的影响,模型中调整气象因素、时间趋势和星期几等变量。 结果 研究期间共纳入因儿童呼吸系统疾病急诊就诊153 995人次,儿童呼吸系统疾病急诊就诊量随O3质量浓度上升而增加。相对于60 μg/m3,O3质量浓度在P25、P50、P75和P95时儿童呼吸系统疾病急诊就诊量单日滞后效应相对危险度(relative risk, RR)及95%置信区间(confidence interval, CI)分别为1.004(1.000~1.008)、1.031(1.016~1.045)、1.062(1.037~1.087)和1.084(1.053~1.115),累积滞后效应RR(95%CI)分别为1.009(1.001~1.013)、1.082(1.046~1.119)、1.185(1.112~1.263)和1.244(1.159~1.336)。O3质量浓度对男孩和女孩呼吸系统疾病急诊就诊量的影响差异无统计学意义。不同疾病中,P25至P95浓度范围O3对急性上呼吸感染、急性下呼吸道感染及肺炎急诊就诊量影响的单日滞后效应RR分别为1.006~1.072、1.006~1.058和1.005~1.060,累积滞后效应RR分别为1.009~1.223、1.003~1.359和1.017~1.450。 结论 合肥市空气O3质量浓度升高可能会增加儿童呼吸系统疾病发病风险。
中图分类号:
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