乳腺癌患者睡眠质量及相关因素分析

doi:10.6040/j.issn.1671-7554.0.2019.042

摘要/Abstract

摘要： 目的调查乳腺癌患者睡眠质量状况,并分析相关因素对睡眠质量的影响。方法选取2018 年 7月至11月就诊的女性乳腺癌患者100例作为病例组,同期行健康筛查的女性200例作为对照组,利用自行设计的一般资料调查表和匹兹堡睡眠质量指数量表(PSQI)收集研究对象人口学特征和睡眠质量,通过查阅病历系统获取患者的疾病相关信息。采用线性回归分析法分析乳腺癌患者睡眠质量的相关因素。结果病例组患者睡眠质量较对照组差(6.46±3.58 vs 4.99±3.06,t=3.512,P<0.001),根据划界分,病例组67.0%的患者睡眠质量判定为差,高于对照组的44.5%(χ2=13.522,P<0.001)。乳房切除手术较未手术(B=2.81,Beta=0.38, 95%CI:0.77~4.85,P=0.007)及保乳手术(B=2.92,Beta=0.40,95%CI:1.40~4.45,P<0.001)的患者睡眠质量差。结论乳腺癌患者的睡眠质量较健康女性差,乳房切除手术是患者睡眠质量差的一个重要影响因素。提示临床应重视对乳腺癌术后患者睡眠质量的评估。

关键词: 乳腺癌, 睡眠质量, 匹兹堡睡眠质量指数, 乳腺癌保乳术, 乳房切除术

Abstract: Objective To investigate the sleep quality of patients with breast cancer and analyze the influencing factors. Methods A total of 100 female breast cancer patients who received breast surgery during Jul. and Nov. 2018 were selected as the case group, and 200 healthy women who received health screening during the same period were selected as the control group. The demographic characteristics and sleep quality of the subjects were collected using a self-designed general data questionnaire and the Pittsburgh Sleep Quality Index(PSQI). Patients disease-related information was obtained from the medical records. The influencing factors of sleep quality were analyzed with linear regression analysis. Results The case group had lower sleep quality than control group(4.99±3.06 vs 6.46±3.58, t=3.512, P<0.001), and 67.0% of the patients and 44.5% of the healthy controls had poor sleep quality(χ2=13.522, P<0.001). Patients who underwent mastectomy had poorer sleep quality than those who did not receive surgery (B=2.81, Beta=0.38, 95% CI: 0.77~4.85, P=0.007)and those who underwent breast-conserving surgery (B=2.92, Beta=0.40, 95% CI: 1.40~4.45, P<0.001). Conclusion Breast cancer patients have poorer sleep quality than healthy women. Mastectomy is an important influencing factor of sleep quality, indicating that attention should be paid to the evaluation of postoperative sleep quality.

Key words: Breast cancer, Sleep quality, Pittsburgh Sleep Quality Index, Breast-conserving surgery, Mastectomy

中图分类号:

R737.9

栾娜,刘丽媛,王斐,周飞,相玉娟,黄淑亚,郑超,于理想,余之刚. 乳腺癌患者睡眠质量及相关因素分析[J]. 山东大学学报 (医学版), 2019, 57(4): 59-64.

LUAN Na, LIU Liyuan, WANG Fei, ZHOU Fei, XIANG Yujuan, HUANG Shuya, ZHENG Chao, YU Lixiang, YU Zhigang. A study of sleep quality of patients with breast cancer and influencing factors[J]. Journal of Shandong University (Health Sciences), 2019, 57(4): 59-64.

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