关键词: 隐匿性脑脊液漏；脑脊液漏；保守治疗；手术治疗

Abstract:

Objective   To  analyze the diagnosis and treatment of 49 cases of latent CSFL after cerebllopontine angle (CPA) tumor surgery. Methods   A retrospective analysis was made on the clinical data of 49 cases of latent CSFL after CPA tumor surgery admitted and treated by Shandong Provincial Hospital Affiliated to Shandong University from January 2006 to January  2013, among which conservative treatment was applied in 32 cases while 17 received operation. The hospital stays, hospital costs, cure rates and relapse rates of conservative and surgical treatments were analyzed and compared. Results   The cases were followed up for 6 to 35 months (mean, 16.50±1.10 months). Average hospital costs had significant difference (t=13.07，P<0.01). The success rate of first conservative treatment was 93.75%(30/32), which was obviously higher than the cure rate of common-type CSFL. The success rate of first operation was 82.35%(14/17).The cure rates of the first treatment and average hospital stays in both treatment groups showed no statistical significance. Conclusion    In the cases of latent CSFL after CPA tumor surgery, SPECT technology is not necessarily applied in the diagnosis, unless the patients choose surgical treatment. Standard conservative treatment shows greater superiority to surgical treatment.

Key words:  Latent cerebrospinal fluid leakage； Cerebrospinal fluid leakage； Conservative treatment； Surgical treatment