关键词: 溃疡性结肠炎;病变范围;Baron分级;黏膜愈合;Logistics回归

Abstract:

Objective   To discuss the predictive effect of Baron index on mucosal healing of ulcerative colitis. Methods   The clinical data of 176 cases of ulcerative colitis treated in Qilu Hospital of Shandong University were analyzed, including gender, age, endoscopic lesions and Baron index. After 1-month treatment with mesalazine, the mucosal healing conditions were evaluated. The relationship between Baron index and mucosal healing was assessed with logistics regression. Results   No significant difference of Baron index was observed in subgroups of different ages and genders (P>0.05). And no statistical correlation was noted between Baron index and severity of lesions (P>0.05). The mucosal healing rates of patients with Baron index 1, 2 and 3 were 66.7%, 38.5% and 0% respectively. The correlation between Baron index and mucosal healing was proved with logistics regression (P<0.001, OR=12.445, 95%CI：4.466～34.680). Conclusion    Baron index can predict mucosal healing of ulcerative colitis.

Key words: Ulcerative colitis; Severity of lesions; Baron index; Mucosal healing; Logistics regression