治疗原发性三叉神经痛 (附142例报告)

山东大学学报(医学版) ›› 2011, Vol. 49 ›› Issue (3): 99-101.

治疗原发性三叉神经痛 (附142例报告)

张良文，王萍，李峰，杨扬，朱树干

山东大学齐鲁医院神经外科，济南 250012

收稿日期:2010-11-06 出版日期:2011-03-10 发布日期:2011-03-10
通讯作者: 朱树干(1952- )，男，教授，博士生导师，主要从事脑肿瘤研究。 E-mail:zlwneurosurgeon@yahoo.com.cn
作者简介:张良文(1972- )，男，副教授，主要从事脑肿瘤与三叉神经痛、面肌痉挛的临床研究。

Treatment of primary trigeminal neuralgia by microvascular decompression: report of 142 cases

ZHANG Liang-wen, WANG Ping, LI Feng, YANG Yang, ZHU Shu-gan

Department of Neurosurgery, Qilu Hospital of Shandong University, Jinan 250012, China

Received:2010-11-06 Online:2011-03-10 Published:2011-03-10

摘要/Abstract

摘要：

目的探讨微血管减压术治疗原发性三叉神经痛(TN)的手术方法及疗效。方法对142例TN患者行微血管减压术，对临床资料进行回顾性分析。结果术后128例(90%)疼痛消失，9例(6.4%)疼痛明显减轻，手术有效率达96.5%。随访期大于2年的82例患者中，74例疼痛完全消除，5例时有疼痛可药物(卡马西平)控制，3例药物不能有效控制。结论 MVD是治疗TN的有效办法；对责任血管的准确判断及合理处理是微血管减压术成功的关键；良好的显微操作能最大程度降低各种手术并发症。

关键词: 三叉神经痛;显微血管减压术；疗效

Abstract:

Objective To explore the method and effectiveness of micro-vascular decompression(MVD) on the treatment of primary trigeminal neuralgia(TN). Methods MVD was carried out on 142 primary TN patients, and the data were retrospectively analyzed. Results Of all cases, total pain relief was achieved in 128 (90%), partial pain relief in 9, and a total of 137(96.5%) profited from MVD. In the 82 cases with a more than 2-year follow-up, pain vanished in 74, pain sometimes occurred in 5, which could be relieved by oral medicine (carbamazepine), and the remaining 3 could not be effectively controlled by medicine. Conclusions MVD is an effective method in treating primary TN. Finding responsible vessels exactly and handling properly are the key to MVD. Skilled manipulation could lower the probability of mortality and complications to the greatest degree.

Key words: Trigeminal neuralgia; Microvascular decompression； Effectiveness

中图分类号:

R651.11

张良文，王萍，李峰，杨扬，朱树干. 治疗原发性三叉神经痛 (附142例报告)[J]. 山东大学学报(医学版), 2011, 49(3): 99-101.

ZHANG Liang-wen, WANG Ping, LI Feng, YANG Yang, ZHU Shu-gan. Treatment of primary trigeminal neuralgia by microvascular decompression: report of 142 cases[J]. JOURNAL OF SHANDONG UNIVERSITY (HEALTH SCIENCES), 2011, 49(3): 99-101.

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